A0A087WUI7 · A0A087WUI7_HUMAN
- ProteinDS cell adhesion molecule
- GeneDSCAM
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1847 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | synapse | |
Biological Process | nervous system development |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A087WUI7
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 1430-1451 | Helical | ||||
Sequence: MLVTISCILVGVLLLFVLLLVV |
Keywords
- Cellular component
Disease & Variants
Variants
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The viewer provides 2,376 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Modified residue (large scale data) | 109 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 1769 | PRIDE | Phosphoserine | ||||
Sequence: S |
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 60-140 | Ig-like | ||||
Sequence: PSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVI | ||||||
Domain | 148-236 | Ig-like | ||||
Sequence: PLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVV | ||||||
Domain | 242-335 | Ig-like | ||||
Sequence: PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARIN | ||||||
Domain | 339-427 | Ig-like | ||||
Sequence: PASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVT | ||||||
Domain | 431-520 | Ig-like | ||||
Sequence: PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLI | ||||||
Domain | 525-618 | Ig-like | ||||
Sequence: PKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT | ||||||
Domain | 622-718 | Ig-like | ||||
Sequence: PAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ | ||||||
Domain | 720-817 | Fibronectin type-III | ||||
Sequence: PPDPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEA | ||||||
Domain | 822-921 | Fibronectin type-III | ||||
Sequence: PPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLED | ||||||
Domain | 926-1022 | Fibronectin type-III | ||||
Sequence: PPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKED | ||||||
Domain | 1026-1120 | Fibronectin type-III | ||||
Sequence: PPAGVKAAAASASMVFVSWLPPLKLNGIIRKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAP | ||||||
Domain | 1120-1212 | Ig-like | ||||
Sequence: PARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQ | ||||||
Domain | 1214-1308 | Fibronectin type-III | ||||
Sequence: PPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGK | ||||||
Domain | 1309-1410 | Fibronectin type-III | ||||
Sequence: EPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPP | ||||||
Region | 1553-1645 | Disordered | ||||
Sequence: LVDVSDARPGTNPTTRRNAKAGPTARNRYASQWTLNRPHPTISAHTLTTDWRLPTPRAAGSVDKESDSYSVSPSQDTDRARSSMVSTESASST | ||||||
Compositional bias | 1560-1602 | Polar residues | ||||
Sequence: RPGTNPTTRRNAKAGPTARNRYASQWTLNRPHPTISAHTLTTD | ||||||
Compositional bias | 1617-1645 | Polar residues | ||||
Sequence: ESDSYSVSPSQDTDRARSSMVSTESASST | ||||||
Compositional bias | 1690-1704 | Polar residues | ||||
Sequence: TDSLTSSTPSESGIC | ||||||
Region | 1690-1718 | Disordered | ||||
Sequence: TDSLTSSTPSESGICRFTASPPKPQDGGR | ||||||
Region | 1806-1847 | Disordered | ||||
Sequence: LPQREGAELGQAAKMSSSQESLLDSRGHLKGNNPYAKSYTLV | ||||||
Compositional bias | 1817-1831 | Polar residues | ||||
Sequence: AAKMSSSQESLLDSR |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,847
- Mass (Da)203,855
- Last updated2014-10-29 v1
- ChecksumC9E25C92006DCBDD
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1560-1602 | Polar residues | ||||
Sequence: RPGTNPTTRRNAKAGPTARNRYASQWTLNRPHPTISAHTLTTD | ||||||
Compositional bias | 1617-1645 | Polar residues | ||||
Sequence: ESDSYSVSPSQDTDRARSSMVSTESASST | ||||||
Compositional bias | 1690-1704 | Polar residues | ||||
Sequence: TDSLTSSTPSESGIC | ||||||
Compositional bias | 1817-1831 | Polar residues | ||||
Sequence: AAKMSSSQESLLDSR |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF042090 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AF042091 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AF064862 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AF064863 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AF064865 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
KF457309 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
KF457311 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
KF457321 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |