A0A087WSH2 · A0A087WSH2_MOUSE
- ProteinRegulator of G-protein signaling 6
- GeneRgs6
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids437 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Variants
Variant ID(s) | Position(s) | Change | Description | Clinical significance | Provenance | ||
---|---|---|---|---|---|---|---|
rs3389261909 | 3 | D>V | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83032097A>T Codon: GAT/GTT Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83032097A>T Locations: - p.Asp3Val (Ensembl:ENSMUST00000186848) - c.8A>T (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389217429 | 62 | I>N | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83098107T>A Codon: ATC/AAC Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83098107T>A Locations: - p.Ile62Asn (Ensembl:ENSMUST00000186848) - c.185T>A (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389246841 | 112 | E>K | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83106564G>A Codon: GAA/AAA Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83106564G>A Locations: - p.Glu112Lys (Ensembl:ENSMUST00000186848) - c.334G>A (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3403508249 | 138 | Q>H | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83110255A>T Codon: CAA/CAT Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83110255A>T Locations: - p.Gln138His (Ensembl:ENSMUST00000186848) - c.414A>T (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389251089 | 149 | K>R | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.11) Somatic: No Accession: NC_000078.7:g.83112742A>G Codon: AAG/AGG Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83112742A>G Locations: - p.Lys149Arg (Ensembl:ENSMUST00000186848) - c.446A>G (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389247182 | 153 | E>K | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83112753G>A Codon: GAA/AAA Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83112753G>A Locations: - p.Glu153Lys (Ensembl:ENSMUST00000186848) - c.457G>A (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389233204 | 154 | R>I | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83112757G>T Codon: AGA/ATA Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83112757G>T Locations: - p.Arg154Ile (Ensembl:ENSMUST00000186848) - c.461G>T (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389251238 | 160 | Q>R | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83112775A>G Codon: CAA/CGA Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83112775A>G Locations: - p.Gln160Arg (Ensembl:ENSMUST00000186848) - c.479A>G (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389222147 | 162 | R>L | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83112781G>T Codon: CGG/CTG Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83112781G>T Locations: - p.Arg162Leu (Ensembl:ENSMUST00000186848) - c.485G>T (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389179842 | 198 | V>I | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83116272G>A Codon: GTA/ATA Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83116272G>A Locations: - p.Val198Ile (Ensembl:ENSMUST00000186848) - c.592G>A (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389251336 | 205 | T>S | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (1) Somatic: No Accession: NC_000078.7:g.83116294C>G Codon: ACC/AGC Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83116294C>G Locations: - p.Thr205Ser (Ensembl:ENSMUST00000186848) - c.614C>G (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs256167247 | 208 | Q>H | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.16) Somatic: No Accession: NC_000078.7:g.83116304G>T Codon: CAG/CAT Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83116304G>T Locations: - p.Gln208His (Ensembl:ENSMUST00000186848) - c.624G>T (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389222114 | 212 | H>L | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83116315A>T Codon: CAC/CTC Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83116315A>T Locations: - p.His212Leu (Ensembl:ENSMUST00000186848) - c.635A>T (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389247118 | 237 | I>N | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83117394T>A Codon: ATT/AAT Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83117394T>A Locations: - p.Ile237Asn (Ensembl:ENSMUST00000186848) - c.710T>A (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389251300 | 314 | Q>* | EVA | ||||
Consequence: stop gained Somatic: No Accession: NC_000078.7:g.83153611C>T Codon: CAG/TAG Consequence type: stop gained Cytogenetic band: 12q Genomic location: NC_000078.7:g.83153611C>T Locations: - p.Gln314Ter (Ensembl:ENSMUST00000186848) - c.940C>T (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs52189734 | 326 | E>Q | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83153647G>C Codon: GAA/CAA Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83153647G>C Locations: - p.Glu326Gln (Ensembl:ENSMUST00000186848) - c.976G>C (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389247127 | 327 | N>I | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83153651A>T Codon: AAT/ATT Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83153651A>T Locations: - p.Asn327Ile (Ensembl:ENSMUST00000186848) - c.980A>T (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389222098 | 363 | S>G | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000078.7:g.83162987A>G Codon: AGT/GGT Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83162987A>G Locations: - p.Ser363Gly (Ensembl:ENSMUST00000186848) - c.1087A>G (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: | |||||||
rs3389251068 | 396 | K>M | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0.01) Somatic: No Accession: NC_000078.7:g.83180442A>T Codon: AAG/ATG Consequence type: missense Cytogenetic band: 12q Genomic location: NC_000078.7:g.83180442A>T Locations: - p.Lys396Met (Ensembl:ENSMUST00000186848) - c.1187A>T (Ensembl:ENSMUST00000186848) Source type: large scale study Cross-references: |