Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model.Mehrabian M., Wen P.Z., Fisler J., Davis R.C., Lusis A.J.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCJ Clin Invest 101:2485-2496 (1998)Mapped to83
SOX9 and SRY binding sites on mouse mXYSRa/Enh13 enhancer redundantly regulate Sox9 expression to varying degrees.Ogawa Y., Terao M., Tsuji-Hosokawa A., Tsuchiya I., Hasegawa M., Takada S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCHum Mol Genet 32:55-64 (2023)Mapped to31
Deletion of Wt1 during early gonadogenesis leads to differences of sex development in male and female adult mice.Torres-Cano A., Portella-Fortuny R., Muller-Sanchez C., Porras-Marfil S., Ramiro-Pareta M., Chau Y.Y., Reina M., Soriano F.X., Martinez-Estrada O.M.View abstractCategoriesFunction, Expression, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCPLoS Genet 18:e1010240-e1010240 (2022)Mapped to99
Embryonic Steroids Control Developmental Programming of Energy Balance.Monica Shih M.C., Huang C.C., Chu H.P., Hsu N.C., Chung B.C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCEndocrinology 162:bqab196-bqab196 (2021)Mapped to99+
Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity.Gannon A.L., O'Hara L., Mason I.J., Jorgensen A., Frederiksen H., Curley M., Milne L., Smith S., Mitchell R.T., Smith L.B.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCFront Endocrinol (Lausanne) 11:599869-599869 (2020)Mapped to17
Placentation defects are highly prevalent in embryonic lethal mouse mutants.Perez-Garcia V., Fineberg E., Wilson R., Murray A., Mazzeo C.I., Tudor C., Sienerth A., White J.K., Tuck E.[...], Hemberger M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCNature 555:463-468 (2018)Cited in1Mapped to99+
Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function.Berthon A., Faucz F.R., Espiard S., Drougat L., Bertherat J., Stratakis C.A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCHum Mol Genet 26:3495-3507 (2017)Mapped to99+
Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice.Tu Z., Wang Q., Cui T., Wang J., Ran H., Bao H., Lu J., Wang B., Lydon J.P.[...], Wang H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCCell Death Differ 23:169-181 (2016)Mapped to99+
Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling.Callier P., Calvel P., Matevossian A., Makrythanasis P., Bernard P., Kurosaka H., Vannier A., Thauvin-Robinet C., Borel C.[...], Nef S.View abstractCategoriesPhenotypes & VariantsSourceMGI: 88582PubMedEurope PMCPLoS Genet. 10:e1004340-e1004340 (2014)Cited in3Mapped to55
Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice.Pitetti J.L., Calvel P., Romero Y., Conne B., Truong V., Papaioannou M.D., Schaad O., Docquier M., Herrera P.L.[...], Nef S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCPLoS Genet 9:e1003160-e1003160 (2013)Mapped to99+
Loss of Wnt5a disrupts primordial germ cell migration and male sexual development in mice.Chawengsaksophak K., Svingen T., Ng E.T., Epp T., Spiller C.M., Clark C., Cooper H., Koopman P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCBiol Reprod 86:1-12 (2012)Mapped to59
A conditional knockout resource for the genome-wide study of mouse gene function.Skarnes W.C., Rosen B., West A.P., Koutsourakis M., Bushell W., Iyer V., Mujica A.O., Thomas M., Harrow J.[...], Bradley A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCNature 474:337-342 (2011)Mapped to99+
XY Sox9 embryonic loss-of-function mouse mutants show complete sex reversal and produce partially fertile XY oocytes.Lavery R., Lardenois A., Ranc-Jianmotamedi F., Pauper E., Gregoire E.P., Vigier C., Moreilhon C., Primig M., Chaboissier M.C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCDev Biol 354:111-122 (2011)Mapped to70
GATA4 deficiency impairs ovarian function in adult mice.Kyronlahti A., Vetter M., Euler R., Bielinska M., Jay P.Y., Anttonen M., Heikinheimo M., Wilson D.B.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCBiol Reprod 84:1033-1044 (2011)Mapped to24
Increased litter size and super-ovulation rate in congenic C57BL mice carrying a polymorphic fragment of NFR/N origin at the Fecq4 locus of chromosome 9.Liljander M., Andersson A., Holmdahl R., Mattsson R.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCGenet Res (Camb) 91:259-265 (2009)Mapped to25
SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages.Chiu S.Y., Asai N., Costantini F., Hsu W.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCPLoS Biol 6:e310-e310 (2008)Mapped to61
Disrupted gonadogenesis and male-to-female sex reversal in Pod1 knockout mice.Cui S., Ross A., Stallings N., Parker K.L., Capel B., Quaggin S.E.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCDevelopment 131:4095-4105 (2004)Mapped to52
Cell-specific knockout of steroidogenic factor 1 reveals its essential roles in gonadal function.Jeyasuria P., Ikeda Y., Jamin S.P., Zhao L., De Rooij D.G., Themmen A.P., Behringer R.R., Parker K.L.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCMol Endocrinol 18:1610-1619 (2004)Mapped to18
Differential requirement for steroidogenic factor-1 gene dosage in adrenal development versus endocrine function.Bland M.L., Fowkes R.C., Ingraham H.A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88582PubMedEurope PMCMol Endocrinol 18:941-952 (2004)Mapped to28