MDMX: a novel p53-binding protein with some functional properties of MDM2.Shvarts A., Steegenga W.T., Riteco N., Van Laar T., Dekker P., Bazuine M., Van Ham R.C.A., Van der Houven van Oordt W., Hateboer G.[...], Jochemsen A.G.View abstractCategoryInteractionSourceMGI: 107934PubMedEurope PMCEMBO J. 15:5349-5357 (1996)Cited in1Mapped to11
MDMX Recruits UbcH5c to Facilitate MDM2 E3 Ligase Activity and Subsequent p53 Degradation <i>In Vivo</i>.Yang J., Jin A., Han J., Chen X., Zheng J., Zhang Y.View abstractCategoryInteractionSourceMGI: 107934PubMedEurope PMCCancer Res 81:898-909 (2021)Mapped to99+
MDMX inhibits casein kinase 1alpha activity and stimulates Wnt signaling.Huang Q., Chen L., Schonbrunn E., Chen J.View abstractCategoriesFunction, PTM / Processing, InteractionSourceMGI: 107934PubMedEurope PMCEMBO J 39:e104410-e104410 (2020)Mapped to38
MDMX acidic domain inhibits p53 DNA binding in vivo and regulates tumorigenesis.Huang Q., Chen L., Yang L., Xie X., Gan L., Cleveland J.L., Chen J.View abstractCategoriesFunction, InteractionSourceMGI: 107934PubMedEurope PMCProc Natl Acad Sci U S A 115:E3368-E3377 (2018)Mapped to28
Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice.Tian H., Tackmann N.R., Jin A., Zheng J., Zhang Y.View abstractCategoriesFunction, InteractionSourceMGI: 107934PubMedEurope PMCJ Biol Chem 292:21614-21622 (2017)Mapped to26
p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis.Tashakori M., Zhang Y., Xiong S., You M.J., Lozano G.View abstractCategoriesFunction, InteractionSourceMGI: 107934PubMedEurope PMCMol Cancer Res 14:56-65 (2016)Mapped to64
Mdm2 RING mutation enhances p53 transcriptional activity and p53-p300 interaction.Clegg H.V., Itahana Y., Itahana K., Ramalingam S., Zhang Y.View abstractCategoryInteractionSourceMGI: 107934PubMedEurope PMCPLoS One 7:e38212-e38212 (2012)Mapped to42
Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability.Pant V., Xiong S., Iwakuma T., Quintas-Cardama A., Lozano G.View abstractCategoryInteractionSourceMGI: 107934PubMedEurope PMCProc Natl Acad Sci U S A 108:11995-12000 (2011)Mapped to37
Regulation of MDM4 (MDMX) function by p76(MDM2): a new facet in the control of p53 activity.Giglio S., Mancini F., Pellegrino M., Di Conza G., Puxeddu E., Sacchi A., Pontecorvi A., Moretti F.View abstractCategoryInteractionSourceMGI: 107934PubMedEurope PMCOncogene 29:5935-5945 (2010)Mapped to48
Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo.Francoz S., Froment P., Bogaerts S., De Clercq S., Maetens M., Doumont G., Bellefroid E., Marine J.C.View abstractCategoryInteractionSourceMGI: 107934PubMedEurope PMCProc Natl Acad Sci U S A 103:3232-3237 (2006)Mapped to36
Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2.Meulmeester E., Maurice M.M., Boutell C., Teunisse A.F., Ovaa H., Abraham T.E., Dirks R.W., Jochemsen A.G.View abstractCategoryInteractionSourceMGI: 107934PubMedEurope PMCMol Cell 18:565-576 (2005)Mapped to23
Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53.Parant J., Chavez-Reyes A., Little N.A., Yan W., Reinke V., Jochemsen A.G., Lozano G.View abstractCategoryInteractionSourceMGI: 107934PubMedEurope PMCNat Genet 29:92-95 (2001)Mapped to26