A0A087WQP2 · A0A087WQP2_MOUSE
- ProteinTransformed mouse 3T3 cell double minute 4
- GeneMdm4
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids110 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Publications for A0A087WQP2
Snrpb is required in murine neural crest cells for proper splicing and craniofacial morphogenesis.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 107934
Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death.
- CategoryFunction
- SourceMGI: 107934
Targeting mechanosensitive MDM4 promotes lung fibrosis resolution in aged mice.
- CategoryFunction
- SourceMGI: 107934
MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism.
- CategoryFunction
- SourceMGI: 107934
MDMX inhibits casein kinase 1alpha activity and stimulates Wnt signaling.
- CategoriesFunction, PTM / Processing, Interaction
- SourceMGI: 107934
Mdm4 controls ureteric bud branching via regulation of p53 activity.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 107934
The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes.
- CategoriesFunction, Expression
- SourceMGI: 107934
Role of smooth muscle cell p53 in pulmonary arterial hypertension.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 107934
MDMX acidic domain inhibits p53 DNA binding in vivo and regulates tumorigenesis.
- CategoriesFunction, Interaction
- SourceMGI: 107934
Inhibition of Mdmx (Mdm4) <i>in vivo</i> induces anti-obesity effects.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 107934
Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice.
- CategoriesFunction, Interaction
- SourceMGI: 107934
Tumorigenesis promotes Mdm4-S overexpression.
- CategoryFunction
- SourceMGI: 107934
p53 pathway is involved in cell competition during mouse embryogenesis.
- CategoryFunction
- SourceMGI: 107934
The p53 inhibitor Mdm4 cooperates with multiple genetic lesions in tumourigenesis.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 107934
Loss of oocytes due to conditional ablation of Murine double minute 2 (Mdm2) gene is p53-dependent and results in female sterility.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 107934