Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells.Zambrowicz B.P., Friedrich G.A., Buxton E.C., Lilleberg S.L., Person C., Sands A.T.View abstractCategoriesSequencesSourceMGI: 107934PubMedEurope PMCNature 392:608-611 (1998)Mapped to99+
Isolation and identification of the human homolog of a new p53-binding protein, Mdmx.Shvarts A., Bazuine M., Dekker P., Ramos Y.F.M., Steegenga W.T., Merckx G., van Ham R.C.A., van der Houven van Oordt W., van der Eb A.J., Jochemsen A.G.View abstractCategoriesSequencesSourceMGI: 107934PubMedEurope PMCGenomics 43:34-42 (1997)Cited in1Mapped to10
MDMX: a novel p53-binding protein with some functional properties of MDM2.Shvarts A., Steegenga W.T., Riteco N., Van Laar T., Dekker P., Bazuine M., Van Ham R.C.A., Van der Houven van Oordt W., Hateboer G.[...], Jochemsen A.G.View abstractCategoriesInteractionSourceMGI: 107934PubMedEurope PMCEMBO J. 15:5349-5357 (1996)Cited in1Mapped to11
Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis.Yao F., Huang S., Liu J., Tan C., Xu M., Wang D., Huang M., Zhu Y., Huang X., He S.View abstractSourceMGI: 107934PubMedEurope PMCCell Death Dis 14:543-543 (2023)Mapped to99+
Snrpb is required in murine neural crest cells for proper splicing and craniofacial morphogenesis.Alam S.S., Kumar S., Beauchamp M.C., Bareke E., Boucher A., Nzirorera N., Dong Y., Padilla R., Zhang S.J.[...], Jerome-Majewska L.A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 107934PubMedEurope PMCDis Model Mech 15:dmm049544-dmm049544 (2022)Mapped to82
Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death.El-Saafin F., Bergamasco M.I., Chen Y., May R.E., Esakky P., Hediyeh-Zadeh S., Dixon M., Wilcox S., Davis M.J.[...], Voss A.K.View abstractSourceMGI: 107934PubMedEurope PMCCell Death Differ 29:1013-1027 (2022)Mapped to99+
A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies.Tiu G.C., Kerr C.H., Forester C.M., Krishnarao P.S., Rosenblatt H.D., Raj N., Lantz T.C., Zhulyn O., Bowen M.E.[...], Barna M.View abstractCategoriesFunctionSourceMGI: 107934PubMedEurope PMCDev Cell 56:2089-2102.e11 (2021)Mapped to99+
Targeting mechanosensitive MDM4 promotes lung fibrosis resolution in aged mice.Qu J., Yang S.Z., Zhu Y., Guo T., Thannickal V.J., Zhou Y.View abstractSourceMGI: 107934PubMedEurope PMCJ Exp Med 218:e20202033-e20202033 (2021)Mapped to7
MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism.Ueda K., Kumari R., Schwenger E., Wheat J.C., Bohorquez O., Narayanagari S.R., Taylor S.J., Carvajal L.A., Pradhan K.[...], Steidl U.View abstractCategoriesFunctionSourceMGI: 107934PubMedEurope PMCCancer Cell 39:529-547.e7 (2021)Mapped to53
MDMX Recruits UbcH5c to Facilitate MDM2 E3 Ligase Activity and Subsequent p53 Degradation <i>In Vivo</i>.Yang J., Jin A., Han J., Chen X., Zheng J., Zhang Y.View abstractCategoriesInteractionSourceMGI: 107934PubMedEurope PMCCancer Res 81:898-909 (2021)Mapped to99+
MDMX inhibits casein kinase 1alpha activity and stimulates Wnt signaling.Huang Q., Chen L., Schonbrunn E., Chen J.View abstractCategoriesFunction, PTM / Processing, InteractionSourceMGI: 107934PubMedEurope PMCEMBO J 39:e104410-e104410 (2020)Mapped to38
Mdm4 controls ureteric bud branching via regulation of p53 activity.Hilliard S.A., Li Y., Dixon A., El-Dahr S.S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 107934PubMedEurope PMCMech Dev 163:103616-103616 (2020)Mapped to99+
The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes.Bowen M.E., McClendon J., Long H.K., Sorayya A., Van Nostrand J.L., Wysocka J., Attardi L.D.View abstractCategoriesFunction, ExpressionSourceMGI: 107934PubMedEurope PMCDev Cell 50:212-228.e6 (2019)Mapped to74
Role of smooth muscle cell p53 in pulmonary arterial hypertension.Wakasugi T., Shimizu I., Yoshida Y., Hayashi Y., Ikegami R., Suda M., Katsuumi G., Nakao M., Hoyano M.[...], Minamino T.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 107934PubMedEurope PMCPLoS One 14:e0212889-e0212889 (2019)Mapped to21
p53 plays a crucial role in endothelial dysfunction associated with hyperglycemia and ischemia.Yokoyama M., Shimizu I., Nagasawa A., Yoshida Y., Katsuumi G., Wakasugi T., Hayashi Y., Ikegami R., Suda M.[...], Minamino T.View abstractCategoriesFunctionSourceMGI: 107934PubMedEurope PMCJ Mol Cell Cardiol 129:105-117 (2019)Mapped to99+
Dysregulation of Mdm2 and Mdm4 alternative splicing underlies motor neuron death in spinal muscular atrophy.Van Alstyne M., Simon C.M., Sardi S.P., Shihabuddin L.S., Mentis G.Z., Pellizzoni L.View abstractCategoriesFunctionSourceMGI: 107934PubMedEurope PMCGenes Dev 32:1045-1059 (2018)Mapped to30
Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells.Si S., Nakajima-Takagi Y., Iga T., Tsuji M., Hou L., Oshima M., Koide S., Saraya A., Yamazaki S.[...], Iwama A.View abstractCategoriesFunctionSourceMGI: 107934PubMedEurope PMCExp Hematol 63:41-51.e1 (2018)Mapped to28
MDMX acidic domain inhibits p53 DNA binding in vivo and regulates tumorigenesis.Huang Q., Chen L., Yang L., Xie X., Gan L., Cleveland J.L., Chen J.View abstractCategoriesFunction, InteractionSourceMGI: 107934PubMedEurope PMCProc Natl Acad Sci U S A 115:E3368-E3377 (2018)Mapped to28
An EZH2-mediated epigenetic mechanism behind p53-dependent tissue sensitivity to DNA damage.Kuser-Abali G., Gong L., Yan J., Liu Q., Zeng W., Williamson A., Lim C.B., Molloy M.E., Little J.B.[...], Yuan Z.M.View abstractCategoriesFunctionSourceMGI: 107934PubMedEurope PMCProc Natl Acad Sci U S A 115:3452-3457 (2018)Mapped to21
Inhibition of Mdmx (Mdm4) <i>in vivo</i> induces anti-obesity effects.Kon N., Wang D., Li T., Jiang L., Qiang L., Gu W.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 107934PubMedEurope PMCOncotarget 9:7282-7297 (2018)Mapped to21
Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice.Tian H., Tackmann N.R., Jin A., Zheng J., Zhang Y.View abstractCategoriesFunction, InteractionSourceMGI: 107934PubMedEurope PMCJ Biol Chem 292:21614-21622 (2017)Mapped to26
Tumorigenesis promotes Mdm4-S overexpression.Pant V., Larsson C.A., Aryal N., Xiong S., You M.J., Quintas-Cardama A., Lozano G.View abstractCategoriesFunctionSourceMGI: 107934PubMedEurope PMCOncotarget 8:25837-25847 (2017)Mapped to17