A0A087WQ41 · A0A087WQ41_MOUSE

  • Protein
    Calcium-activated potassium channel subunit alpha-1
  • Gene
    Kcnma1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Molecular Functionpotassium channel activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Calcium-activated potassium channel subunit alpha-1
  • Alternative names
    • BK channel
    • BKCA alpha
    • Calcium-activated potassium channel, subfamily M subunit alpha-1
    • K(VCA)alpha
    • KCa1.1

Gene names

    • Name
      Kcnma1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    A0A087WQ41

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane86-108Helical
Transmembrane179-197Helical
Transmembrane217-235Helical
Transmembrane300-321Helical
Transmembrane336-355Helical
Transmembrane367-385Helical

Keywords

  • Cellular component

PTM/Processing

Keywords

Expression

Gene expression databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-61Disordered
Compositional bias26-61Polar residues
Domain181-396Ion transport
Domain406-523Calcium-activated potassium channel slowpoke-like RCK
Domain546-633Calcium-activated potassium channel BK alpha subunit
Region699-729Disordered
Compositional bias708-726Polar residues
Domain780-903Calcium-activated potassium channel slowpoke-like RCK
Domain998-1118Ca2+-activated K+ channel Slowpoke-like C-terminal
Compositional bias1128-1159Polar residues
Region1128-1178Disordered
Compositional bias1160-1178Basic and acidic residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,178
  • Mass (Da)
    130,991
  • Last updated
    2014-10-29 v1
  • Checksum
    52EED529C1747FF2
MANGGGGGGGSSGGGGGGGGGSGLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEVVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDVTDPKRIKKCGCRRLEDEQPPTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRPNRPKSRESRDKQNRKEMVYR

Computationally mapped potential isoform sequences

There are 29 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q08460KCMA1_MOUSEKcnma11209
E3VRY6E3VRY6_MOUSEKcnma11113
E3VRY9E3VRY9_MOUSEKcnma11192
E3VRZ4E3VRZ4_MOUSEKcnma11113
F6ZSN2F6ZSN2_MOUSEKcnma11108
E9Q9P4E9Q9P4_MOUSEKcnma11053
A0A286YD59A0A286YD59_MOUSEKcnma11171
A0A286YD35A0A286YD35_MOUSEKcnma11209
A0A286YD36A0A286YD36_MOUSEKcnma1357
A0A286YCW3A0A286YCW3_MOUSEKcnma11112
A0A286YCP1A0A286YCP1_MOUSEKcnma11185
A0A286YCQ2A0A286YCQ2_MOUSEKcnma11142
A0A286YCF5A0A286YCF5_MOUSEKcnma11119
A0A286YCI9A0A286YCI9_MOUSEKcnma11115
A0A286YDU9A0A286YDU9_MOUSEKcnma11142
A0A286YDM6A0A286YDM6_MOUSEKcnma11242
A0A286YDR7A0A286YDR7_MOUSEKcnma11146
A0A286YE30A0A286YE30_MOUSEKcnma11165
A0A087WQN5A0A087WQN5_MOUSEKcnma11239
A0A286YCZ9A0A286YCZ9_MOUSEKcnma11178
A0A286YDB5A0A286YDB5_MOUSEKcnma1477
A0A087WQE1A0A087WQE1_MOUSEKcnma1634
A0A286YDC1A0A286YDC1_MOUSEKcnma11175
A0A087WRS4A0A087WRS4_MOUSEKcnma11236
A0A087WSQ4A0A087WSQ4_MOUSEKcnma1191
J3QN27J3QN27_MOUSEKcnma11132
J3QMT8J3QMT8_MOUSEKcnma11135
J3QP84J3QP84_MOUSEKcnma11059
A0A1D5RMA3A0A1D5RMA3_MOUSEKcnma1332

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias26-61Polar residues
Compositional bias708-726Polar residues
Compositional bias1128-1159Polar residues
Compositional bias1160-1178Basic and acidic residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp