A high-resolution map of human evolutionary constraint using 29 mammals.Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S., Kheradpour P., Ernst J., Jordan G.[...], Kellis M.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainThorbeckeCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 478:476-482 (2011)Cited in99+99+
Regulation of the mammalian elongation cycle by subunit rolling: a eukaryotic-specific ribosome rearrangement.Budkevich T.V., Giesebrecht J., Behrmann E., Loerke J., Ramrath D.J., Mielke T., Ismer J., Hildebrand P.W., Tung C.S.[...], Spahn C.M.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (6.90 ANGSTROMS) OF RIBOSOME, FUNCTION, SUBUNIT, SUBCELLULAR LOCATIONCategoriesFunction, Interaction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 158:121-131 (2014)Cited in11Mapped to3
Structural basis for stop codon recognition in eukaryotes.Brown A., Shao S., Murray J., Hegde R.S., Ramakrishnan V.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.45 ANGSTROMS) OF 2-24 OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 524:493-496 (2015)Cited in634Mapped to1
Decoding mammalian ribosome-mRNA states by translational GTPase complexes.Shao S., Murray J., Brown A., Taunton J., Ramakrishnan V., Hegde R.S.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.75 ANGSTROMS) OF RIBOSOME, FUNCTION, SUBCELLULAR LOCATION, SUBUNITCategoriesFunction, Interaction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 167:1229-1240 (2016)Cited in675Mapped to2
Structural and mutational analysis of the ribosome-arresting human XBP1u.Shanmuganathan V., Schiller N., Magoulopoulou A., Cheng J., Braunger K., Cymer F., Berninghausen O., Beatrix B., Kohno K.[...], Beckmann R.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.00 ANGSTROMS) OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCElife 8:0-0 (2019)Cited in654Mapped to8
The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.Acosta-Reyes F., Neupane R., Frank J., Fernandez I.S.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.10 ANGSTROMS) OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 38:e102226-e102226 (2019)Cited in704
Mechanism of ribosome stalling during translation of a poly(A) tail.Chandrasekaran V., Juszkiewicz S., Choi J., Puglisi J.D., Brown A., Shao S., Ramakrishnan V., Hegde R.S.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (2.80 ANGSTROMS) OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Struct. Mol. Biol. 26:1132-1140 (2019)Cited in603
The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism.Abaeva I.S., Vicens Q., Bochler A., Soufari H., Simonetti A., Pestova T.V., Hashem Y., Hellen C.U.T.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.49 ANGSTROMS) OF 2-24 OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Rep. 33:108476-108476 (2020)Cited in637Mapped to9
A molecular network of conserved factors keeps ribosomes dormant in the egg.Leesch F., Lorenzo-Orts L., Pribitzer C., Grishkovskaya I., Roehsner J., Chugunova A., Matzinger M., Roitinger E., Belacic K.[...], Pauli A.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (2.30 ANGSTROMS) OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 613:712-720 (2023)Cited in7999+Mapped to40
Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.Brown Z.P., Abaeva I.S., De S., Hellen C.U.T., Pestova T.V., Frank J.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.50 ANGSTROMS) OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 41:e110581-e110581 (2022)Cited in305Mapped to5
N<sup>6</sup>-methyladenosine in 5' UTR does not promote translation initiation.Guca E., Alarcon R., Palo M.Z., Santos L., Alonso-Gil S., Davyt M., de Lima L.H.F., Boissier F., Das S.[...], Ignatova Z.View abstractCategoriesStructureSourcePDB: 8P03, PDB: 8P09PubMedEurope PMCMol Cell 84:584-595.e6 (2024)Cited in8Mapped to28
The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center.Coelho J.P.L., Yip M.C.J., Oltion K., Taunton J., Shao S.View abstractCategoriesStructureSourcePDB: 8SCBPubMedEurope PMCNat Chem Biol 20:877-884 (2024)Mapped to75
Modulation of GluA2-gamma5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.Gangwar S.P., Yen L.Y., Yelshanskaya M.V., Korman A., Jones D.R., Sobolevsky A.I.View abstractCategoriesStructureSourcePDB: 8BHFPubMedEurope PMCNat Struct Mol Biol 30:1481-1494 (2023)Cited in7Mapped to65
NAC controls cotranslational N-terminal methionine excision in eukaryotes.Gamerdinger M., Jia M., Schloemer R., Rabl L., Jaskolowski M., Khakzar K.M., Ulusoy Z., Wallisch A., Jomaa A.[...], Deuerling E.View abstractCategoriesStructureSourcePDB: 8P2KPubMedEurope PMCScience 380:1238-1243 (2023)Cited in12Mapped to77
Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation.Hopfler M., Absmeier E., Peak-Chew S.Y., Vartholomaiou E., Passmore L.A., Gasic I., Hegde R.S.View abstractCategoriesStructureSourcePDB: 8BPOPubMedEurope PMCMol Cell 83:2290-2302.e13 (2023)Cited in2Mapped to37
Molecular basis of the TRAP complex function in ER protein biogenesis.Jaskolowski M., Jomaa A., Gamerdinger M., Shrestha S., Leibundgut M., Deuerling E., Ban N.View abstractCategoriesStructureSourcePDB: 8BTKPubMedEurope PMCNat Struct Mol Biol 30:770-777 (2023)Cited in11Mapped to80
Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative.Pauwels E., Shewakramani N.R., De Wijngaert B., Camps A., Provinciael B., Stroobants J., Kalies K.U., Hartmann E., Maes P.[...], Das K.View abstractCategoriesStructureSourcePDB: 8B5L, PDB: 8B6CPubMedEurope PMCSci Adv 9:eadf0797-eadf0797 (2023)Cited in7Mapped to41
Mechanism of an intramembrane chaperone for multipass membrane proteins.Smalinskaite L., Kim M.K., Lewis A.J.O., Keenan R.J., Hegde R.S.View abstractCategoriesStructureSourcePDB: 7TM3, PDB: 7TUTPubMedEurope PMCNature 611:161-166 (2022)Cited in98Mapped to371
Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.Hilal T., Killam B.Y., Grozdanovic M., Dobosz-Bartoszek M., Loerke J., Buerger J., Mielke T., Copeland P.R., Simonovic M., Spahn C.M.T.View abstractCategoriesStructureSourcePDB: 7ZJW, PDB: 7ZJXPubMedEurope PMCScience 376:1338-1343 (2022)Cited in4831Mapped to7
Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine.Arango D., Sturgill D., Yang R., Kanai T., Bauer P., Roy J., Wang Z., Hosogane M., Schiffers S., Oberdoerffer S.View abstractCategoriesStructureSourcePDB: 7UCJ, PDB: 7UCKPubMedEurope PMCMol. Cell 82:2797-2814 (2022)Cited in566Mapped to3
Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.Loveland A.B., Svidritskiy E., Susorov D., Lee S., Park A., Zvornicanin S., Demo G., Gao F.B., Korostelev A.A.View abstractCategoriesStructureSourcePDB: 7TORPubMedEurope PMCNat Commun 13:2776-2776 (2022)Cited in8Mapped to99+
Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.Jomaa A., Gamerdinger M., Hsieh H.H., Wallisch A., Chandrasekaran V., Ulusoy Z., Scaiola A., Hegde R.S., Shan S.O.[...], Deuerling E.View abstractCategoriesStructureSourcePDB: 7QWQ, PDB: 7QWR, PDB: 7QWSPubMedEurope PMCScience 375:839-844 (2022)Cited in7Mapped to41
New tools for automated cryo-EM single-particle analysis in RELION-4.0.Kimanius D., Dong L., Sharov G., Nakane T., Scheres S.H.W.View abstractCategoriesStructureSourcePDB: 8RJB, PDB: 8RJC, PDB: 8RJDPubMedEurope PMCBiochem J 478:4169-4185 (2021)Mapped to63
Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation.Koga Y., Hoang E.M., Park Y., Keszei A.F.A., Murray J., Shao S., Liau B.B.View abstractCategoriesStructureSourcePDB: 7MDZPubMedEurope PMCJ Am Chem Soc 143:13473-13477 (2021)Cited in5Mapped to71
Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle.Jomaa A., Eitzinger S., Zhu Z., Chandrasekar S., Kobayashi K., Shan S.O., Ban N.View abstractCategoriesStructureSourcePDB: 7OBRPubMedEurope PMCCell Rep. 36:109350-109350 (2021)Cited in15Mapped to43