A0A087NA24 · A0A087NA24_9SPHN
- ProteinMethylamine dehydrogenase (amicyanin)
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids181 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.
Catalytic activity
- 2 oxidized [amicyanin] + methylamine + H2O = 2 reduced [amicyanin] + formaldehyde + NH4+ + 2 H+
Pathway
One-carbon metabolism; methylamine degradation; formaldehyde from methylamine: step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 84 | substrate | |||
Active site | 109 | Tryptophylquinone 6'-substrate hemiaminal intermediate | |||
Active site | 128 | Proton acceptor | |||
Binding site | 156-158 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | outer membrane-bounded periplasmic space | |
Molecular Function | aliphatic amine dehydrogenase activity | |
Molecular Function | methylamine dehydrogenase (amicyanin) activity | |
Biological Process | amine metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethylamine dehydrogenase (amicyanin)
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingobium
Accessions
- Primary accessionA0A087NA24
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for disulfide bond, modified residue, cross-link.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 75↔140 | ||||
Disulfide bond | 81↔113 | ||||
Disulfide bond | 88↔171 | ||||
Disulfide bond | 90↔138 | ||||
Disulfide bond | 91↔135 | ||||
Disulfide bond | 98↔129 | ||||
Modified residue | 109 | Tryptophylquinone | |||
Cross-link | 109↔160 | Tryptophan tryptophylquinone (Trp-Trp) | |||
Disulfide bond | 130↔161 | ||||
Keywords
- PTM
Interaction
Subunit
Heterotetramer of two light and two heavy chains.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 68-178 | Methylamine/Aralkylamine dehydrogenase light chain C-terminal | |||
Sequence similarities
Belongs to the aromatic amine dehydrogenase light chain family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length181
- Mass (Da)19,332
- Last updated2014-10-29 v1
- MD5 Checksum81A2F7D2738F60F89D6D0708AFFA9A16
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JPPQ01000069 EMBL· GenBank· DDBJ | KFL45977.1 EMBL· GenBank· DDBJ | Genomic DNA |