A0A087CNY3 · A0A087CNY3_9BIFI

Function

function

This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.
    EC:3.4.23.36 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; lipoprotein biosynthesis (signal peptide cleavage).

Features

Showing features for active site.

118320406080100120140160180
TypeIDPosition(s)Description
Active site127
Active site140

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionaspartic-type endopeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Lipoprotein signal peptidase
  • EC number
  • Alternative names
    • Prolipoprotein signal peptidase
    • Signal peptidase II
      (SPase II
      )

Gene names

    • Name
      lspA
    • ORF names
      BREU_1868

Organism names

Accessions

  • Primary accession
    A0A087CNY3

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane68-86Helical
Transmembrane93-111Helical
Transmembrane131-156Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the peptidase A8 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    183
  • Mass (Da)
    19,189
  • Last updated
    2014-10-29 v1
  • Checksum
    F1694BA3965CFECA
MTNQQGRLRMRVAVFACVSAAALIVDQLTKAWALAALSSGQTIRVIPGLLSLTLVHNPGASLGMGSNATWIISLLAIVASCALLYFGVRSVSLKWTVSLSLAFAGAFGNLIDRVMYADGFLNGKVVDFLNYGWSVGNVADIYLVAAGVAIVVLILLNEPFSTADADEAHANNAESDGTKVDAE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JGZK01000013
EMBL· GenBank· DDBJ
KFI84983.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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