A0A087C6V0 · A0A087C6V0_9BIFI

Function

function

Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP: step 1/1.

Features

Showing features for binding site, site, active site.

Type
IDPosition(s)Description
Binding site101-106dCTP (UniProtKB | ChEBI)
Site116-117Important for bifunctional activity
Binding site119dCTP (UniProtKB | ChEBI)
Binding site127-129dCTP (UniProtKB | ChEBI)
Active site129Proton donor/acceptor
Binding site148dCTP (UniProtKB | ChEBI)
Binding site162dCTP (UniProtKB | ChEBI)
Binding site174dCTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctiondCTP deaminase (dUMP-forming) activity
Molecular FunctiondCTP deaminase activity
Molecular Functionnucleotide binding
Biological ProcessdUMP biosynthetic process
Biological ProcessdUTP biosynthetic process
Biological Processnucleobase-containing small molecule interconversion

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dCTP deaminase, dUMP-forming
  • EC number
  • Alternative names
    • Bifunctional dCTP deaminase:dUTPase
    • DCD-DUT

Gene names

    • Name
      dcd
    • ORF names
      BMON_1413

Organism names

Accessions

  • Primary accession
    A0A087C6V0

Proteomes

Interaction

Subunit

Homotrimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the dCTP deaminase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    193
  • Mass (Da)
    21,368
  • Last updated
    2014-10-29 v1
  • Checksum
    B709E60C3BDB8D0E
MLLSDHDILDARDHGHLALEPWTPEMVQPASIDVRLDRFFRLFNNHAYTYVDPAENQGALTEQFEVKPGEPWILHPGEFALGSTWERITLDASIAARLEGKSSLGRLGILTHSTAGFIDPGFDGHITLELSNVSTLPVKLWPGMKIGQMCFFSLSSPAEHPYGSAGTGSHYQGQRGPTPSRSYINFYKADIDD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JGZE01000003
EMBL· GenBank· DDBJ
KFI79000.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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