A0A087C6V0 · A0A087C6V0_9BIFI
- ProteindCTP deaminase, dUMP-forming
- Genedcd
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids193 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
Catalytic activity
- dCTP + 2 H2O = dUMP + NH4+ + diphosphate
Pathway
Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP: step 1/1.
Features
Showing features for binding site, site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 101-106 | dCTP (UniProtKB | ChEBI) | |||
Site | 116-117 | Important for bifunctional activity | |||
Binding site | 119 | dCTP (UniProtKB | ChEBI) | |||
Binding site | 127-129 | dCTP (UniProtKB | ChEBI) | |||
Active site | 129 | Proton donor/acceptor | |||
Binding site | 148 | dCTP (UniProtKB | ChEBI) | |||
Binding site | 162 | dCTP (UniProtKB | ChEBI) | |||
Binding site | 174 | dCTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | dCTP deaminase (dUMP-forming) activity | |
Molecular Function | dCTP deaminase activity | |
Molecular Function | nucleotide binding | |
Biological Process | dUMP biosynthetic process | |
Biological Process | dUTP biosynthetic process | |
Biological Process | nucleobase-containing small molecule interconversion |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namedCTP deaminase, dUMP-forming
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Bifidobacteriales > Bifidobacteriaceae > Bifidobacterium
Accessions
- Primary accessionA0A087C6V0
Proteomes
Interaction
Structure
Sequence
- Sequence statusComplete
- Length193
- Mass (Da)21,368
- Last updated2014-10-29 v1
- ChecksumB709E60C3BDB8D0E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JGZE01000003 EMBL· GenBank· DDBJ | KFI79000.1 EMBL· GenBank· DDBJ | Genomic DNA |