A0A086P4W7 · A0A086P4W7_SPHHM

Function

function

Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion.

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.
Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site54Zn2+ (UniProtKB | ChEBI); catalytic
Active site56Proton donor
Binding site79Zn2+ (UniProtKB | ChEBI); catalytic
Binding site89Zn2+ (UniProtKB | ChEBI); catalytic
Binding site159NADP+ (UniProtKB | ChEBI)
Binding site173substrate
Binding site175NADP+ (UniProtKB | ChEBI)
Binding site189substrate
Binding site201NADP+ (UniProtKB | ChEBI)
Binding site205NADP+ (UniProtKB | ChEBI)
Binding site209substrate
Binding site212substrate
Binding site256substrate
Binding site258-264NADP+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function5-amino-6-(5-phosphoribosylamino)uracil reductase activity
Molecular Functiondiaminohydroxyphosphoribosylaminopyrimidine deaminase activity
Molecular Functionmetal ion binding
Biological Processriboflavin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Riboflavin biosynthesis protein RibD

Including 2 domains:

  • Recommended name
    Diaminohydroxyphosphoribosylaminopyrimidine deaminase
  • EC number
  • Short names
    DRAP deaminase
  • Alternative names
    • Riboflavin-specific deaminase
  • Recommended name
    5-amino-6-(5-phosphoribosylamino)uracil reductase
  • EC number
  • Alternative names
    • HTP reductase

Gene names

    • ORF names
      BV98_003620

Organism names

Accessions

  • Primary accession
    A0A086P4W7

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-128CMP/dCMP-type deaminase

Sequence similarities

In the C-terminal section; belongs to the HTP reductase family.
In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    327
  • Mass (Da)
    35,043
  • Last updated
    2014-10-29 v1
  • Checksum
    F6078D79E855C008
MADPADDRRFMAAAIALSERGRGLSTPNPNVGCLIVRDGAVVGRGWTQKGGRPHAEAQALDQALDQARGATAYVTLEPCFHLSPRGPRCADLMVRAGVKRVVIALRDPDPRTDGQGAAYLRAHDIDVEMGLMAREAAAAMSGFVLRQTLGRPAVTLKLGLSLDGCIALKDGASRWITGEAARAHAHLERARHDAILVGGGTLRADAPRLDVRLKGLEDRSPRRLLITRGPALKGWETVSQPDDIAALAQVDHLLIEGGSATAAAFLRADLVDRLLLYRAPILIGSGLPGIGDIGLSDLAQAHGGWRLTDERRLGEDRLEVYERRRTA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JFZA02000060
EMBL· GenBank· DDBJ
KFG88435.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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