A0A086JEJ7 · A0A086JEJ7_TOXGO

  • Protein
    Putative rRNA methyltransferase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site, active site.

1981100200300400500600700800900
Type
IDPosition(s)Description
Binding site62S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site64S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site82S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site98S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site123S-adenosyl-L-methionine (UniProtKB | ChEBI)
Active site163Proton acceptor

GO annotations

AspectTerm
Cellular Componentnucleolus
Cellular Componentpreribosome, large subunit precursor
Molecular FunctionrRNA (guanine) methyltransferase activity
Molecular FunctionrRNA (uridine-2'-O-)-methyltransferase activity
Biological Processmaturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological Processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative rRNA methyltransferase
  • EC number
  • Alternative names
    • 2'-O-ribose RNA methyltransferase SPB1 homolog

Gene names

    • ORF names
      TGP89_207990

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • p89
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Apicomplexa > Conoidasida > Coccidia > Eucoccidiorida > Eimeriorina > Sarcocystidae > Toxoplasma

Accessions

  • Primary accession
    A0A086JEJ7

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain29-206Ribosomal RNA methyltransferase FtsJ
Region240-275Disordered
Compositional bias259-274Acidic residues
Domain309-452DUF3381
Region398-421Disordered
Region500-544Disordered
Compositional bias502-517Basic and acidic residues
Compositional bias525-544Acidic residues
Region556-581Disordered
Region594-641Disordered
Compositional bias608-627Acidic residues
Region653-783Disordered
Compositional bias700-767Basic and acidic residues
Domain761-965Ribosomal RNA methyltransferase SPB1-like C-terminal
Region926-981Disordered
Compositional bias958-981Basic residues

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    981
  • Mass (Da)
    109,418
  • Last updated
    2014-10-29 v1
  • Checksum
    C29FF2C023C36C38
MAGGDSHRKKKTGKQRLDKFYHLAKEQGYRARSAFKLLQLSQRFRLFEKSCASVVDLCAAPGGWLQVAAKHCPVATTIVGVDLVPIAPIRGVQTFTGDITTPQCAAKLRKLVKFGEVDLVLHDGSPNMGTDWSVDAFSQNVLVLCAAKLACQLLAAGATFVSKVFRSSDYAALLYVLQTLFERVDATKPQASRAVSAEIFVVCRGFRKPPVLDERLFDPKHVFLQGSDDGDAPAAAQKAVRRSGGDDGAAQRLAEGDEADDGEAAEEEEEDEEREGIFFGSRGGRKGQFAELVRRRLKRHRNGDLLAGLRRVTVDEFFRSKDPTTLLVEQAREIFFQTPAVALEEAVRNHRLTTPETLACLADVQVLGKAELAALLKWRFRVKKDVFLALGLRTHATAEKPPAGANDDGEERDRDEADSAEIDEELTRLHASVTRREAKQQKRQAQKQKQLEMRKKLTRGAFFDEAEGPLDPDLFQFDRKAIDLLEKKEAKMVDAELLLTGGEDDDGNRRGRHADGGEGEAVVAGSESEAEEEGSLEELDDVDRMEVELTLAHRLKKQREAEALAAGPKKKETRREKVTGEWVNELQAFRSAMQRRAGEALAERRRAEEEEDDEEENEEDAEDASKEVFEDEAPAGLRKATAADRWFGQPIFAGLESPGVQDESDAECSPIGRSAGDVASDEQRLSDSEASSGDDEVETEATSDVMRELADEELPAVPLSEKQKQKKRRATQAEKERNRKQRRQATDGIVGPDFDDDDDKTGLRGKTRIEEVPPPPAFQRPTDPEEIAHIQALGSLMVQKSTRMDLLDGAYNRYAFNDDALPEWFAEDEEAHTRPELPVTKELMREYRQKLLDISRRPIRKVREARARKKMREQRRLQKVKSQVAAVAESTGFTEASKARAIDKIARKARHAEEKRGKDYVVTRRVGGGKLAQKKAGKKGGGNNRVKLVDRRLKKDKRAMKAAMKKKGGQRRGLKKKSRKS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias259-274Acidic residues
Compositional bias502-517Basic and acidic residues
Compositional bias525-544Acidic residues
Compositional bias608-627Acidic residues
Compositional bias700-767Basic and acidic residues
Compositional bias958-981Basic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AEYI02002043
EMBL· GenBank· DDBJ
KFG30565.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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