A0A085NMF2 · A0A085NMF2_9BILA
- ProteinArachidonate--CoA ligase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids2934 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphateThis reaction proceeds in the forward direction.
- (E)-hexadec-2-enoate + ATP + CoA = (2E)-hexadecenoyl-CoA + AMP + diphosphateThis reaction proceeds in the forward direction.
- 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + ATP + CoA = 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-CoA + AMP + diphosphateThis reaction proceeds in the forward direction.
- 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + ATP + CoA = 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-CoA + AMP + diphosphateThis reaction proceeds in the forward direction.
- 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA = 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphateThis reaction proceeds in the forward direction.
- ATP + CoA + hexadecanoate = AMP + diphosphate + hexadecanoyl-CoAThis reaction proceeds in the forward direction.
Features
Showing features for active site, binding site, site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 2133 | Nucleophile | ||||
Sequence: H | ||||||
Binding site | 2135 | substrate | ||||
Sequence: K | ||||||
Active site | 2333 | Proton donor/acceptor | ||||
Sequence: H | ||||||
Binding site | 2335 | substrate | ||||
Sequence: K | ||||||
Site | 2358 | Interaction with DNA | ||||
Sequence: S |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum | |
Cellular Component | membrane | |
Cellular Component | nucleus | |
Cellular Component | ribonucleoprotein complex | |
Cellular Component | ribosome | |
Molecular Function | long-chain fatty acid-CoA ligase activity | |
Molecular Function | phosphoric diester hydrolase activity | |
Molecular Function | structural constituent of ribosome | |
Biological Process | DNA repair | |
Biological Process | translation |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameArachidonate--CoA ligase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Enoplea > Dorylaimia > Trichinellida > Trichuridae > Trichuris
Accessions
- Primary accessionA0A085NMF2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 1488-1510 | Helical | ||||
Sequence: FWLSLGISVLLISAINLRVLFFI | ||||||
Transmembrane | 1546-1569 | Helical | ||||
Sequence: FAISLCAILLLCDFVVDLFVQHNI | ||||||
Transmembrane | 1581-1602 | Helical | ||||
Sequence: WPLFMNVSICLFTGAAFLFIFF | ||||||
Transmembrane | 1614-1634 | Helical | ||||
Sequence: FVRYIVKLTVSIAESLYFSLW |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 2654-2899 | Glycosyl transferase CAP10 | ||||
Sequence: WLPDIDFILNLGDWPLELRRRQSMPPVPIISWCGSADSLDIVLPSYEVMLNILKSNLSYNQDLLRVSELRQISWENKKSKAFWRGRDSRKERLLLVNISRSHPDLLDAALTHFFFFNNEIPIYGPAVATVPFQDFFKYKYQVNVDGTVAAYRLTLLLAGNSLVLKQDSDYYEHYYRGMQQGVHYVPFKADLSNLLEKIEWAKRHPKKVRKIISNAHAFLKDNVMPREVYCYNIEVLLRYKKILKHP |
Sequence similarities
Belongs to the ATP-dependent AMP-binding enzyme family.
Belongs to the eukaryotic ribosomal protein eL34 family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,934
- Mass (Da)332,886
- Last updated2014-10-29 v1
- ChecksumF7B773F8DAD480CF