A0A085N178 · A0A085N178_9BILA

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

119112004006008001,0001,2001,4001,6001,800
TypeIDPosition(s)Description
Binding site247Zn2+ (UniProtKB | ChEBI); catalytic
Active site248
Binding site251Zn2+ (UniProtKB | ChEBI); catalytic
Binding site257Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentextracellular space
Cellular Componentmembrane
Molecular Functioncalcium ion binding
Molecular Functionmetalloendopeptidase activity
Molecular Functionserine-type endopeptidase activity
Molecular Functiontransmembrane transporter activity
Molecular Functionzinc ion binding
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Metalloendopeptidase
  • EC number

Gene names

    • ORF names
      M514_24601

Organism names

  • Taxonomic identifier
  • Strain
    • DCEP-RM93F
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Enoplea > Dorylaimia > Trichinellida > Trichuridae > Trichuris

Accessions

  • Primary accession
    A0A085N178

Proteomes

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane1316-1337Helical
Transmembrane1357-1379Helical
Transmembrane1436-1456Helical
Transmembrane1468-1486Helical
Transmembrane1676-1698Helical
Transmembrane1710-1729Helical
Transmembrane1741-1761Helical
Transmembrane1767-1788Helical
Transmembrane1800-1824Helical
Transmembrane1830-1851Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-26
ChainPRO_500510622227-1911Metalloendopeptidase
Disulfide bond217↔239
Disulfide bond219↔220

Keywords

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain144-355Peptidase M12A
Domain357-488CUB
Domain489-601CUB
Domain601-641EGF-like
Domain644-760CUB
Domain804-916CUB
Domain917-1033CUB
Domain1285-1856Major facilitator superfamily (MFS) profile
Region1517-1545Disordered

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,911
  • Mass (Da)
    213,214
  • Last updated
    2014-10-29 v1
  • Checksum
    BB1550B93B99C8D2
MTWSTFGQLTLLVTLTGCSLWSLYNAKKWTTEELLNSRFPYLSSNDLYLDVSKAGGFIADIVLSREDVEAIRMLRNNSLRRANHRHPSIISSGAPCHQCFAVKGHVIGKECEHFDLPALFSSFPAITTRTIGDAIAAPQLVVPSAFGSMESFRTKFWRTLAVGGGGNRFSSRNHSSLGDHHALFRRAMNHWENYTCVSFVPRTSEDVSYIVFTIAECGCCSFVGKRGEGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDLYVDIFYKNIQQGQDYNFEKLKPSEVNSLGQSYDFASIMHYARDTFSRAMYLDTILPKPDSSTHERPEIGQRIRLSPGDIIQTNTLYKCAKCGQTFHEASGIFSSPDYDNKVKSQGEPIHCEWRINTARGHHILLNFTYISIPDSVDCSGDSFLEVRDGPYAKSPLIGRYCGKHVEPLIITSNSHRVWIQYHVAHASLEDAPKKNALKEKKKRRGFAANFEVICGGNITADNGVIENPNYPYDYTPNSDCVWYITVPEDYQVAVIFSMFQLEQHEDCIYDYVEFREGHADDGDVLARVCGYSLPNSIKSNSNKMRVRFGSDASVEKAGFSFNFIKEFDECKTTNHGCRHKCVNTLGGYRCECDIGYELHSDGKSCEDACGGYLKGENGSLTSPNFPNLYPNKKRCVWEIKAHSQYRIFLNFTHFDLEGVLTNCEYDYIKVTSVDGDGEVAKVHGQFCGRIAPQFLLTSETSHLRIEFVTDSSVQKSGFAAVYFTDRDECEVDNGGCEQICKNMIGSYVCECESGYILASDGHHCKEGGCKFELNAAFGQLTSPSYPEDYPNDKECIWHFVTTPGHRLQLDFIEFEIEPHQDCAYDRIELYDGSSIDSPSLGKYCGPKAPEKITSSKNELYMFFHSDSSVQRKGFQAHYTSVCGGTLRAERSVGYVYSHAMYGGSNYENRVACEWTLLAEEGMSVEIQFTNFELEEEVHCEYDYVEVYDGESENSMRLGRFCGNKLPSMFISSGSVLRVRFRADDTVTAKGFVYEYFLTDQLLEQVDCLLWCSSFPPECSCACVYVKLHAIHHLDRLPHGLTIDASSTLVEWCLRLPANNHQIATNGHCDDQAKEQQIYCLHGPTMVHGRHAAVECLTSNSSSISALSHSFSTLVEFKESSKQGLRLATKEFSDWFDEKDSHVTCHYSIPEDIEMQPCSDNMSNFSPISLQVHFVAHKSSPAFSSHFENGKLHNDSGVYDVEETVIIVPLQECDEKIKALMVDYDKTCTLREEELIAEALITPPDGGWGWVIVAALFANLLILDGVELSAGQALLPILTEHFSSTPSAVSLIFSLQSSFYYFAGPFSGALVNAFGCRCVALGGALLCAAGFFLSTFATSITYLYFTYGVLAEVVKSRQVFILSEIFEKQDCKEPLGKGTGMGAIFLCGLSTVSQYFESRRGLATAISLCGAGAGTFIMPPIITLLTEYYHWRHVMLLIAGIQLHNLVFAALYRNLTPTKKQVVEVERRLSVILSAEFNQNIESADEGKGRKQMESSETSDSSLKEKKYSTVAENGRVSPILHQKTQRALSVTAAPIERFTGRQMSLTVDLERAKVHDEQELRKLSYASIVTVNRPMNRFDSLYEGAIPDSTTAQSIKETVPVDRMAESIPRIMQKKRKRFSVVLRNVLRDTFSIRLFASPTYLLFTICYVLSTIGFFVPFLYLPSHAEMLGSSAEMGSFLVSIIGIVNTFCRILWGWVADRPSVDAMHMINCANLVAGTSTVVLPYLKFYPELVAYCVFFGAGIASLISQRSVALLKFVGMKNLTIALGSIMMCMGFACLGGQPLAGYLFEISGNYNAAFGVSGGLMVMAGILGFSLNKIHSWEISKMQAFDKPLSSSRKTAESSREAKSSSSSVVCRLRHMLKMKFAPLLCSKASV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KL367578
EMBL· GenBank· DDBJ
KFD63224.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp