A0A085GHB3 · A0A085GHB3_EWIA3

Function

function

Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Bacterial outer membrane biogenesis; LPS O-antigen biosynthesis.
Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site146Mg2+ (UniProtKB | ChEBI)
Binding site211Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentGram-negative-bacterium-type cell wall
Cellular Componentplasma membrane
Molecular Functionglycosyltransferase activity
Molecular Functionmagnesium ion binding
Molecular Functionmanganese ion binding
Molecular FunctionUDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity
Biological Processcell wall macromolecule biosynthetic process
Biological Processcell wall organization
Biological Processenterobacterial common antigen biosynthetic process
Biological ProcessO antigen biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase
  • EC number
  • Alternative names
    • UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase
    • Undecaprenyl-phosphate GlcNAc-1-phosphate transferase

Gene names

    • Name
      wecA
    • ORF names
      GEAM_1378

Organism names

Accessions

  • Primary accession
    A0A085GHB3

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein
Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-22Helical
Transmembrane43-61Helical
Transmembrane67-83Helical
Transmembrane95-120Helical
Transmembrane126-146Helical
Transmembrane153-172Helical
Transmembrane178-195Helical
Transmembrane207-229Helical
Transmembrane235-257Helical
Transmembrane278-305Helical
Transmembrane311-334Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the glycosyltransferase 4 family. WecA subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    341
  • Mass (Da)
    37,934
  • Last updated
    2014-10-29 v1
  • Checksum
    09AC5D702803EA7E
MQEYIIIFFSALATLFVARKVARRVGLVDKPNARKHHDGHIPLVGGVSIYLSIWVLFFLQPSWFPNFIVYIVCASMLLIVGVLDDRFDLPVRPRLLLQVIVAIIMMYSGLYLATLGNILFGYEIRLGFIGYFVTILAVISAINAFNMVDGIDGLLGALSCVSFASLGIVFYLHGRLELAQWCICLMIACIPYILLNLGVPWGRKFKVFMGDAGSTLIGFTMIWLLVVATQGADSVIHPVTALWLISVPLMDMVRVMISRMRRGDSPFKPDREHLHHILLNYGFKHSTALMIVLAISISFSGVGIIANQLNVSQFGVLALFVVCFLIFVSCINTLSKKSKLK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JMPJ01000039
EMBL· GenBank· DDBJ
KFC83108.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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