A0A085B714 · A0A085B714_9FLAO
- ProteinPhosphoserine aminotransferase
- GeneserC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids351 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
Catalytic activity
- 4-(phosphooxy)-L-threonine + 2-oxoglutarate = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate
Cofactor
Note: Binds 1 pyridoxal phosphate per subunit.
Pathway
Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.
Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 3/5.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 41 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 75-76 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
Binding site | 101 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
Binding site | 149 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
Binding site | 168 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
Binding site | 191 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
Binding site | 233-234 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | O-phospho-L-serine:2-oxoglutarate aminotransferase activity | |
Molecular Function | pyridoxal phosphate binding | |
Biological Process | L-serine biosynthetic process | |
Biological Process | pyridoxine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoserine aminotransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Weeksellaceae > Chryseobacterium group > Chryseobacterium
Accessions
- Primary accessionA0A085B714
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Modified residue | 192 | N6-(pyridoxal phosphate)lysine | |||
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 5-344 | Aminotransferase class V | |||
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length351
- Mass (Da)38,488
- Last updated2014-10-29 v1
- Checksum47D04062790732B0
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JPLZ01000009 EMBL· GenBank· DDBJ | KFC18259.1 EMBL· GenBank· DDBJ | Genomic DNA |