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A0A085AHE6 · A0A085AHE6_9ENTR

Function

function

Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; NAD+ biosynthesis; NAD+ from deamido-NAD+ (ammonia route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site46-53ATP (UniProtKB | ChEBI)
Binding site52Mg2+ (UniProtKB | ChEBI)
Binding site140deamido-NAD+ (UniProtKB | ChEBI); ligand shared between two neighboring subunits; in other chain
Binding site160ATP (UniProtKB | ChEBI)
Binding site165Mg2+ (UniProtKB | ChEBI)
Binding site173deamido-NAD+ (UniProtKB | ChEBI); ligand shared between two neighboring subunits; in other chain
Binding site180deamido-NAD+ (UniProtKB | ChEBI); ligand shared between two neighboring subunits
Binding site189ATP (UniProtKB | ChEBI)
Binding site211ATP (UniProtKB | ChEBI)
Binding site260-261deamido-NAD+ (UniProtKB | ChEBI); ligand shared between two neighboring subunits; in other chain

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionglutaminase activity
Molecular Functionmetal ion binding
Molecular FunctionNAD+ synthase (glutamine-hydrolyzing) activity
Molecular FunctionNAD+ synthase activity
Biological ProcessNAD biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NH(3)-dependent NAD(+) synthetase
  • EC number

Gene names

    • Name
      nadE
    • ORF names
      GTGU_00788

Organism names

Accessions

  • Primary accession
    A0A085AHE6

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain23-265NAD/GMP synthase

Sequence similarities

Belongs to the NAD synthetase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    275
  • Mass (Da)
    30,594
  • Last updated
    2014-10-29 v1
  • MD5 Checksum
    A5DBF55E07396EB7A7CD2115437FEAE7
MTLQHEIIRTLGAKPHIDPDAEIRRSVDFLKDYLKTYSFLNTLVLGISGGQDSTLTGKLCQMAISELREETGNSALQFIAVRLPFGVQADEQDCQDAIDFIKPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTKGVVVGTDHAAEAVTGFFTKYGDGGTDINPIYRLNKRQGKQLLAVLGCPEHLYKKAPTADLEDDRPSLPDEAALGVTYANIDDYLEGKKLDDSIAKIIEGWYTRTEHKRRPPITVFDDFWKK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JMTB01000037
EMBL· GenBank· DDBJ
KFC09641.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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