A0A081V3I0 · A0A081V3I0_BURCE

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentNADH dehydrogenase complex
Cellular Componentplasma membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH:ubiquinone reductase (non-electrogenic) activity
Molecular Functionquinone binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase subunit A
  • EC number
  • Alternative names
    • NADH dehydrogenase I subunit A
    • NDH-1 subunit A
    • NUO1

Gene names

    • Name
      ndhC
    • Synonyms
      nuoA
    • ORF names
      C5615_13650
      , DM43_5060
      , DPR02_31450
      , E3D37_22025
      , JAO13_18245
      , NCTC10661_06148
      , VL15_25750
      , WS90_34680
      , WT26_15710

Organism names

  • Taxonomic identifier
  • Strains
    • 871
    • DWS 37UF10B-2
    • LK29
    • MSMB1302
    • MSMB1184WGS
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia > Burkholderia cepacia complex

Accessions

  • Primary accession
    A0A081V3I0

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-26Helical
Transmembrane61-82Helical
Transmembrane88-111Helical

Keywords

PTM/Processing

Keywords

Interaction

Subunit

NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the complex I subunit 3 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    119
  • Mass (Da)
    13,511
  • Last updated
    2014-10-29 v1
  • Checksum
    82C36D136F2B2FF0
MNLAAYYPVLLFLLVGTGLGIALVSIGKLLGPNKPDVEKNAPYECGFEAFEDARMKFDVRYYLVAILFIIFDLETAFLFPWGVALRDIGWPGFIAMMIFLLEFLLGFAYIWKKGGLDWE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP013443
EMBL· GenBank· DDBJ
AOK17309.1
EMBL· GenBank· DDBJ
Genomic DNA
JPGD01000004
EMBL· GenBank· DDBJ
KGC04566.1
EMBL· GenBank· DDBJ
Genomic DNA
LDWR01000045
EMBL· GenBank· DDBJ
KML51931.1
EMBL· GenBank· DDBJ
Genomic DNA
LOYH01000107
EMBL· GenBank· DDBJ
KVK72333.1
EMBL· GenBank· DDBJ
Genomic DNA
JAEDXG010000016
EMBL· GenBank· DDBJ
MBH9698379.1
EMBL· GenBank· DDBJ
Genomic DNA
PUIQ01000015
EMBL· GenBank· DDBJ
PQP18215.1
EMBL· GenBank· DDBJ
Genomic DNA
QLUZ01000026
EMBL· GenBank· DDBJ
RAQ02213.1
EMBL· GenBank· DDBJ
Genomic DNA
UARD01000044
EMBL· GenBank· DDBJ
SQA57684.1
EMBL· GenBank· DDBJ
Genomic DNA
SNSQ01000026
EMBL· GenBank· DDBJ
TEU44031.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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