A0A076YU68 · A0A076YU68_STRAG

Function

function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.

Features

Showing features for active site, binding site.

1712100200300400500600700
TypeIDPosition(s)Description
Active site376Proton acceptor; specific for D-alanine
Binding site470substrate
Active site603Proton acceptor; specific for L-alanine
Binding site652substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentmembrane
Molecular Functionacyltransferase activity, transferring groups other than amino-acyl groups
Molecular Functionalanine racemase activity
Molecular Functionpyridoxal phosphate binding
Biological ProcessD-alanine biosynthetic process
Biological Processresponse to antibiotic

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alanine racemase
  • EC number

Gene names

    • Name
      vanT

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 2113
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus

Accessions

  • Primary accession
    A0A076YU68

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-33Helical
Transmembrane39-60Helical
Transmembrane80-99Helical
Transmembrane119-138Helical
Transmembrane147-166Helical
Transmembrane186-205Helical
Transmembrane217-237Helical
Transmembrane243-261Helical
Transmembrane273-292Helical
Transmembrane307-328Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue376N6-(pyridoxal phosphate)lysine

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain582-711Alanine racemase C-terminal

Sequence similarities

Belongs to the alanine racemase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    712
  • Mass (Da)
    79,772
  • Last updated
    2014-10-29 v1
  • Checksum
    BD0CF72D73EFFEDD
MTKNESYSGIDYFRFIAALLIVAIHTSPLSSFSETGNFIFTRIVARVAVPFFFMTSGFFLISRYTCNAEKLGAFIKKTTLIYGVAILLYIPINVYNGYFKMDNLLPNIIKDIVFDGTLYHLWYLPASIIGAAIAWYLVKKVHYRKAFLIASILYIIGLFGDSYYGIVKSVSCLNVFYNLIFQLTDYTRNGIFFAPIFFVLGGYISDSQNRLSLKRSIVGFIVCFALMFGEALTLHHFDIQKHDSMYVLLLPSVYCLFNLLLHFRGKRRTGLRTISLIIYIIHPFMIVVIRLFAKLLHLQSLLVENSLVHYIAVCFASVVLAVVITALLSSLKPKKAKHTADTDRAYLEINLNNLEHNVNTLQKAMSPKCELMAVVKAEAYGHGMYEVTTYLEQIGVSSFAVATIDEGIRLRKYGISSEILILGYTSPSRAKELCKYELTQTLIDYRYSLLLNKQGYDIKAHIKIDTGMHRLGFSTEDKDKILAAFSLKHIKVAGIFTHLCAADSLEENDVAFTNKQIGSFYKVLDWLKSSGLNIPKVHIQSSYGLLNYPELECDYIRVGVALYGVLSSTNDKTKLELDLRPVLSLKAKVVLIRKIKQGESVGYSRAFTATRDSLIAILPIGYADGFPRNLSCGNSYVLIGGRQAPIVGKICMDQLAVDVTDIPNVKTGSIATLIGKDGKEEITAPMVAESAESITNELLSRMGHRLNIIRRA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KF697366
EMBL· GenBank· DDBJ
AJQ17025.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp