A0A076YU68 · A0A076YU68_STRAG
- ProteinAlanine racemase
- GenevanT
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids712 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
Catalytic activity
- L-alanine = D-alanine
Cofactor
Pathway
Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 376 | Proton acceptor; specific for D-alanine | ||||
Sequence: K | ||||||
Binding site | 470 | substrate | ||||
Sequence: R | ||||||
Active site | 603 | Proton acceptor; specific for L-alanine | ||||
Sequence: Y | ||||||
Binding site | 652 | substrate | ||||
Sequence: M |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | membrane | |
Molecular Function | acyltransferase activity, transferring groups other than amino-acyl groups | |
Molecular Function | alanine racemase activity | |
Molecular Function | pyridoxal phosphate binding | |
Biological Process | D-alanine biosynthetic process | |
Biological Process | response to antibiotic |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlanine racemase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus
Accessions
- Primary accessionA0A076YU68
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 12-33 | Helical | ||||
Sequence: YFRFIAALLIVAIHTSPLSSFS | ||||||
Transmembrane | 39-60 | Helical | ||||
Sequence: IFTRIVARVAVPFFFMTSGFFL | ||||||
Transmembrane | 80-99 | Helical | ||||
Sequence: LIYGVAILLYIPINVYNGYF | ||||||
Transmembrane | 119-138 | Helical | ||||
Sequence: YHLWYLPASIIGAAIAWYLV | ||||||
Transmembrane | 147-166 | Helical | ||||
Sequence: FLIASILYIIGLFGDSYYGI | ||||||
Transmembrane | 186-205 | Helical | ||||
Sequence: YTRNGIFFAPIFFVLGGYIS | ||||||
Transmembrane | 217-237 | Helical | ||||
Sequence: IVGFIVCFALMFGEALTLHHF | ||||||
Transmembrane | 243-261 | Helical | ||||
Sequence: DSMYVLLLPSVYCLFNLLL | ||||||
Transmembrane | 273-292 | Helical | ||||
Sequence: TISLIIYIIHPFMIVVIRLF | ||||||
Transmembrane | 307-328 | Helical | ||||
Sequence: LVHYIAVCFASVVLAVVITALL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Modified residue | 376 | N6-(pyridoxal phosphate)lysine | ||||
Sequence: K |
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 582-711 | Alanine racemase C-terminal | ||||
Sequence: VLSLKAKVVLIRKIKQGESVGYSRAFTATRDSLIAILPIGYADGFPRNLSCGNSYVLIGGRQAPIVGKICMDQLAVDVTDIPNVKTGSIATLIGKDGKEEITAPMVAESAESITNELLSRMGHRLNIIRR |
Sequence similarities
Belongs to the alanine racemase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length712
- Mass (Da)79,772
- Last updated2014-10-29 v1
- ChecksumBD0CF72D73EFFEDD
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KF697366 EMBL· GenBank· DDBJ | AJQ17025.1 EMBL· GenBank· DDBJ | Genomic DNA |