A0A075GAY0 · A0A075GAY0_9ARCH

Function

function

Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Co2+ (UniProtKB | Rhea| CHEBI:48828 )

Note: Binds 2 Zn2+ or Co2+ ions per subunit.

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis.
Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 5/5.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site118Zn2+ 1 (UniProtKB | ChEBI)
Active site120
Binding site142Zn2+ 1 (UniProtKB | ChEBI)
Binding site142Zn2+ 2 (UniProtKB | ChEBI)
Active site174Proton acceptor
Binding site175Zn2+ 2 (UniProtKB | ChEBI)
Binding site198Zn2+ 1 (UniProtKB | ChEBI)
Binding site392Zn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncobalt ion binding
Molecular Functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Molecular Functionsequence-specific DNA binding
Molecular Functionzinc ion binding
Biological Processarginine biosynthetic process via ornithine
Biological Processlysine biosynthetic process via aminoadipic acid

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative [LysW]-lysine/[LysW]-ornithine hydrolase
  • EC number

Gene names

    • Name
      argE1
    • Synonyms
      lysK

Organism names

Accessions

  • Primary accession
    A0A075GAY0

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-75HTH asnC-type

Sequence similarities

Belongs to the peptidase M20A family. LysK subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    424
  • Mass (Da)
    46,845
  • Last updated
    2014-10-29 v1
  • Checksum
    1EC17C2FB4975DD6
MDDIDKTIIKILTKDSRTPNTEIAQQVNLSESSVRARIEKLVSSGAIKNFTITLSDSHLTLLENALKIYSPSGQEKDISDFLFDTLTNLGFSNVHRDSANNVFGEIGSGSPTLLLCGHMDTVPGQINVQIKDNTLYGRGASDAKSSLISMMIAASSFKDKLNSGKIIFSAVTDEEGTGQGIRELLKANLQLDCAIFGEPSGIDKITVGYKGRYSVKFTCDTPPVHASAPWMSHNAIELLFLLWNEIQTEIQTNDDNHYKQITSCLTQIEGGTADNVMPGNSTLICDIRYPFGYNPDQITQKISETVSNYNSKYTFDENPKSTFNYEIIDSTPAFECSKSSVISRSVSRAIIKKLDLKPKFVNKTGTGDMNLLGNQMNIPVLTYGPGNPHLSHTSNEHIMIDEFLTSIDIYHDSIENLFDLLQRI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KF900546
EMBL· GenBank· DDBJ
AIE98827.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help