A0A075GAY0 · A0A075GAY0_9ARCH
- ProteinPutative [LysW]-lysine/[LysW]-ornithine hydrolase
- GeneargE1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids424 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
Catalytic activity
- [amino-group carrier protein]-C-terminal-gamma-(L-lysyl)-L-glutamate + H2O = [amino-group carrier protein]-C-terminal-L-glutamate + L-lysine
Cofactor
Co2+ (UniProtKB | Rhea| CHEBI:48828 )
Note: Binds 2 Zn2+ or Co2+ ions per subunit.
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis.
Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 5/5.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 118 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Active site | 120 | ||||
Binding site | 142 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 142 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Active site | 174 | Proton acceptor | |||
Binding site | 175 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 198 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 392 | Zn2+ 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | cobalt ion binding | |
Molecular Function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | |
Molecular Function | sequence-specific DNA binding | |
Molecular Function | zinc ion binding | |
Biological Process | arginine biosynthetic process via ornithine | |
Biological Process | lysine biosynthetic process via aminoadipic acid |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative [LysW]-lysine/[LysW]-ornithine hydrolase
- EC number
Gene names
Organism names
- Taxonomic lineageArchaea > Nitrososphaerota > environmental samples
Accessions
- Primary accessionA0A075GAY0
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length424
- Mass (Da)46,845
- Last updated2014-10-29 v1
- Checksum1EC17C2FB4975DD6
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KF900546 EMBL· GenBank· DDBJ | AIE98827.1 EMBL· GenBank· DDBJ | Genomic DNA |