A0A075AYI1 · A0A075AYI1_ROZAC
- ProteinInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1042 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
Catalytic activity
- 1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP
GO annotations
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Fungi incertae sedis > Cryptomycota > Cryptomycota incertae sedis > Rozella
Accessions
- Primary accessionA0A075AYI1
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 340-549 | ATP-grasp | ||||
Sequence: EELNKNLGIDLGNMTNFSRENVIQIDKDTIMVGKQRLEKPFVEKPVDGEDHNIYIYYPESMGGGVRKLFRKVGNKSSEFFPDEWEIRKEGSFIYETFIDVEKAEDIKVYTIGPYYAHAETRKSPVVDGIVRRNTDGKEVRHLTDLSEEEQELARRVSMAFGQTICGFDLVRCGSKSMVIDVNGWSFVKGNDNYYDMCAKIMSQTFLKIAR |
Sequence similarities
Belongs to the histidine acid phosphatase family. VIP1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,042
- Mass (Da)120,389
- Last updated2014-10-01 v1
- ChecksumDDE1933D5B800656
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KE560848 EMBL· GenBank· DDBJ | EPZ35342.1 EMBL· GenBank· DDBJ | Genomic DNA |