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A0A074YMV5 · A0A074YMV5_AURSE

Function

function

Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Note: Binds 1 divalent metal cation per subunit.

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functionmetal ion binding
Molecular FunctionN(6)-L-threonylcarbamoyladenine synthase activity
Biological Processmitochondrial tRNA threonylcarbamoyladenosine modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    N(6)-L-threonylcarbamoyladenine synthase
  • EC number

Gene names

    • ORF names
      AUEXF2481DRAFT_36335

Organism names

Accessions

  • Primary accession
    A0A074YMV5

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain106-456Gcp-like

Sequence similarities

Belongs to the KAE1 / TsaD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    498
  • Mass (Da)
    54,542
  • Last updated
    2014-10-01 v1
  • MD5 Checksum
    A65F7B326C97C445E76FA150F54740A6
MRVTSAAKAIYRTIQGPEAAGNRLSRILKLFVRPTSQNVRTLMLSPLRTFTRAIPPVRSYGVALHRRTLLTLAIETSCDDTSVAIVEKHKDASATLHFHKKVTANTAAYNGIHPVVALESHQSSLAPLLQEALTHLPPSQVDSDPRRTLYHGTTSRMKPDFISATRGPGMRSNLSVGLDAGKALAVAWDIPVLGIHHMQAHALTPRLVSALESRPASGPNFPFLSALVSGGHSMLIESTGLTDHRILATTGDIALGDCLDKAARAILPPHLVVPPYGRALERFAFPGGASDYHYTAPAKRDVELARRVTKWGWGLGAPLAESKNGSSSRKMVYSFSGLLSSIERFVKYEFDHQTSTISRRLRQPGQLSNDERRDMAREVMRVAFEHLASRVLLYLSSLPSQEAAKVSSVVVSGGVAANSFLRHVMRSFLDVRGYQHVELWFPPIELCTDNAAMIGWAGIEMWEAGWRSQLSVRPIKTWSMDPSADDGGILGVEGWLEL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KL584751
EMBL· GenBank· DDBJ
KEQ99025.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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