A0A074RIQ5 · A0A074RIQ5_9AGAM

Function

function

Proteolytically removes the C-terminal three residues of farnesylated proteins.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic side chains and P3' is any C-terminal residue.
    EC:3.4.24.84 (UniProtKB | ENZYME | Rhea)

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

148350100150200250300350400450
TypeIDPosition(s)Description
Binding site305Zn2+ (UniProtKB | ChEBI); catalytic
Active site306
Binding site309Zn2+ (UniProtKB | ChEBI); catalytic
Binding site388Zn2+ (UniProtKB | ChEBI); catalytic
Active site392Proton donor

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Biological ProcessCAAX-box protein processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    CAAX prenyl protease
  • EC number

Gene names

    • ORF names
      V565_172080

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 123E
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Cantharellales > Ceratobasidiaceae > Rhizoctonia

Accessions

  • Primary accession
    A0A074RIQ5

Proteomes

Subcellular Location

Endoplasmic reticulum membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane90-109Helical
Transmembrane129-156Helical
Transmembrane177-196Helical
Transmembrane202-222Helical
Transmembrane318-337Helical
Transmembrane357-380Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain49-232CAAX prenyl protease 1 N-terminal
Domain236-461Peptidase M48

Sequence similarities

Belongs to the peptidase M48A family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    483
  • Mass (Da)
    54,857
  • Last updated
    2014-10-01 v1
  • Checksum
    D1999615DA26CD31
MTKNPIAALQAGVENQLGFISTEFINWQGYVLAFSWGVWAFETYLTYRQFPNYSRPHPPTALKSHFTDEVFNKSQRYGKDKARFSLVSKLYSQLLETGMITLGAFPWAWKVSGSLLARFGYGPEYEITHSIAFGTVLFYLTTIPNLPLSIYSTFVLEEKHGFNKMTPQLFVADTLKGWVVGFAIGAPFMAAFLKIVDWAGQSFVPWLMTFMITFQLAMVVLYPTVIQPLFNKLSPLETGLLRTRIEGLASRLSFPLTDLYVIDGSKRSAHSNAYFYGLPWSKHIVLFDTLIKKSEPAELEAVLAHELGHWKYSHPMKLMLVSQIHLLALFSVFPPFMRSWPLLASFGFPIGPESRPPVLVTFLLYQMVITPIESIVGFLINALSRRFEYQADQFACELDAQGLGGEKEPGKTEEESTMRARLGRALVALHAENLSTVWVDWMYSAYHHSHPTLTERLRAMEVFANQNGRPKVSFRFGHPLWSS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AZST01000872
EMBL· GenBank· DDBJ
KEP46996.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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