A0A074J9W4 · A0A074J9W4_9RHOB

Function

function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionundecaprenyl-diphosphatase activity
Biological Processcell wall organization
Biological Processdephosphorylation
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape
Biological Processresponse to antibiotic

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Undecaprenyl-diphosphatase
  • EC number
  • Alternative names
    • Bacitracin resistance protein
    • Undecaprenyl pyrophosphate phosphatase

Gene names

    • Name
      uppP
    • ORF names
      TP2_05625

Organism names

  • Taxonomic identifier
  • Strain
    • DSM 10166
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Paracoccaceae > Thioclava

Accessions

  • Primary accession
    A0A074J9W4

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane40-58Helical
Transmembrane76-93Helical
Transmembrane105-123Helical
Transmembrane135-153Helical
Transmembrane211-233Helical
Transmembrane245-264Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the UppP family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    265
  • Mass (Da)
    29,018
  • Last updated
    2014-10-01 v1
  • Checksum
    73247372C73468C7
MNYLNDVLLGVIEGITEFLPISSTGHLILAEHWLGTRSDTYNIVIQAGAILAVTLIYWRRLMELLFNWREPENRDYLAKLTVAFLITAVLGLIVKKMGFELPTTIQPVAWALVIGGFWMLFAERVADRQADNSTIFWRVAIAVGIAQIVAGIFPGTSRSATTIFVAMLLGTSNRAAATEFAFLVGIPTMYAASGYELLKQFTSGSAQSEDWTGLGIAFVVSTVTAFIAVKWLLGYIQGHRFTIFAIYRILFGGLLLTLAGLGVLG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AUND01000012
EMBL· GenBank· DDBJ
KEO54406.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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