A0A074J9W4 · A0A074J9W4_9RHOB
- ProteinUndecaprenyl-diphosphatase
- GeneuppP
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids265 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
Miscellaneous
Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
Catalytic activity
- di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + phosphate + H+
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | undecaprenyl-diphosphatase activity | |
Biological Process | cell wall organization | |
Biological Process | dephosphorylation | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape | |
Biological Process | response to antibiotic |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUndecaprenyl-diphosphatase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Paracoccaceae > Thioclava
Accessions
- Primary accessionA0A074J9W4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 40-58 | Helical | |||
Transmembrane | 76-93 | Helical | |||
Transmembrane | 105-123 | Helical | |||
Transmembrane | 135-153 | Helical | |||
Transmembrane | 211-233 | Helical | |||
Transmembrane | 245-264 | Helical | |||
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length265
- Mass (Da)29,018
- Last updated2014-10-01 v1
- Checksum73247372C73468C7
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AUND01000012 EMBL· GenBank· DDBJ | KEO54406.1 EMBL· GenBank· DDBJ | Genomic DNA |