A0A074J2R7 · A0A074J2R7_9RHOB

Function

function

Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i6A).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, site.

TypeIDPosition(s)Description
Binding site18-25ATP (UniProtKB | ChEBI)
Binding site20-25substrate
Site109Interaction with substrate tRNA
Site131Interaction with substrate tRNA

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular FunctiontRNA dimethylallyltransferase activity
Biological ProcesstRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA dimethylallyltransferase
  • EC number
  • Alternative names
    • Dimethylallyl diphosphate:tRNA dimethylallyltransferase
      (DMAPP:tRNA dimethylallyltransferase
      ; DMATase
      )
    • Isopentenyl-diphosphate:tRNA isopentenyltransferase
      (IPP transferase
      ; IPPT
      ; IPTase
      )

Gene names

    • Name
      miaA
    • ORF names
      TP2_09390

Organism names

  • Taxonomic identifier
  • Strain
    • DSM 10166
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Paracoccaceae > Thioclava

Accessions

  • Primary accession
    A0A074J2R7

Proteomes

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the IPP transferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    296
  • Mass (Da)
    32,622
  • Last updated
    2014-10-01 v1
  • Checksum
    2F4F9511F27D1EA5
MRPILPEIPTHLPVLIAGPTASGKSALALELAERDGGIVVNADALQVWSCWRVLSARPSVDEESRAPHRLYGHKHPGEPYSVGHWLREIAPLLEAHNAGGPRSIIVGGTGLYFTALTEGLAEIPETPPAIRAAADARRAAEGHEGMLDELDPVTRARIDPLNPMRVQRAWEVMRATGEGLATWQDRTPAPLLPLAGCTPLLLSPDRDWLAERIDRRFDLMLEGGALDEVRAIAPDWDPDALWARAIGAPELVAYLRGALDLETARNHAQAASRQYAKRQRTWFRSRMKAWHKIAYA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AUND01000034
EMBL· GenBank· DDBJ
KEO51681.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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