A0A073JQA1 · A0A073JQA1_LIMRT

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site60Zn2+ 1 (UniProtKB | ChEBI)
Binding site62Zn2+ 1 (UniProtKB | ChEBI)
Binding site75Zn2+ 1 (UniProtKB | ChEBI)
Binding site78Zn2+ 1 (UniProtKB | ChEBI)
Binding site449Mg2+ (UniProtKB | ChEBI)
Binding site451Mg2+ (UniProtKB | ChEBI)
Binding site453Mg2+ (UniProtKB | ChEBI)
Binding site818Zn2+ 2 (UniProtKB | ChEBI)
Binding site892Zn2+ 2 (UniProtKB | ChEBI)
Binding site899Zn2+ 2 (UniProtKB | ChEBI)
Binding site902Zn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentDNA-directed RNA polymerase complex
Molecular FunctionDNA binding
Molecular FunctionDNA-directed 5'-3' RNA polymerase activity
Molecular Functionmagnesium ion binding
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit beta'
  • EC number
  • Short names
    RNAP subunit beta'
  • Alternative names
    • RNA polymerase subunit beta'
    • Transcriptase subunit beta'

Gene names

    • Name
      rpoC
    • ORF names
      B5F04_04410
      , B5G22_03305
      , BFD03_07385
      , C5O77_03610
      , DB325_06545
      , FOD75_02215
      , GIX74_04000
      , GIX76_00235
      , HHK02_05230
      , JVX33_07125
      , LR3_03245
      , LRLP16767_LR202_00065

Organism names

Accessions

  • Primary accession
    A0A073JQA1

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain224-503RNA polymerase N-terminal

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,211
  • Mass (Da)
    135,392
  • Last updated
    2014-10-01 v1
  • Checksum
    48CB810ADA1278FD
MIDVNKFESMQIGLASPDKIRSWSYGEVKKPETINYRTLKPEKQGLFDERIFGPTKDYECACGKYKRIRYKGRVCDRCGVEVTSAKVRRERMGHIELAAPVSHIWYFKGIPSRMGLVLDMSPRSLEEVIYFASYVVLDPGDTPLEKKQLLTEAEYRDKKAEYGDRFKAEMGAAAIQKLLADVDLEKEAAELKEELKEATGQKRTRAIRRLDILEAFIKSGNKPEWMVMDVIPVMPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLKLQAPGIIVQNEKRMLQEAVDALIDNGRRGRPVAGPGNRPLKSLSHLLKGKQGRFRQNLLGKRVDYSGRSVIDVGPSLKLNQMGLPVPMALELFKPFIMHELVKRGLSANVKAAKRKIDRSDDDVFDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPILVSGKSMRLHPLVCSAYNADFDGDQMAIHVPLSDEAQAEARLLMLAAHHILSPRDGEPIVSPSQDMVIGNYYMTTEDKGREGEGMIFKDTDEAELAYRNDYVSLQTRVGVQVSAFPEKPFTDEQRGKIMVTTVGKLLFNRIMPKDFAYINEPTDANIQNGVDDRFFLEPGQDIHEYLENAPLVPPFKKGFLSDLIAEVYKRYKVTKTSQFLDRIKDLGYYESTISGLTTAMSDIHDLPEKPEILDKAQKQVALITKQFRRGLITDDERYERVIGAWNDAKDEVQNKLIEHMDIHNPINMMSDSGARGNISNFTQLAGMRGLMASPNGKIMELPVKSNFYEGLSVLEMFISSHGARKGMTDTALKTANSGYLTRRLVDVAQDVVVREKDCGTDRGLEVTAITNGNEMIEPLYDRIMGRYTMKSVFDPKTGEKIVGKNVLIDEEMAQKIVDAGVKKVTIRSAFTCNTEHGVCERCYGRNAATGDRVEAGEAVGTVAAQSIGEPGTQLTLRNFHTGGVAGNDDITQGLPRIQEIVEARNPKGRATITEVTGEVVSIEENPAERTKDITIKGETDTRTYTLPITARMKVAEGDFIHRGAPLNEGSIDPKELIQVRDVLSTETYLLSQVQGVYRMQGIDLLDKHVEIMIRQMMRKVRVMDPGDTDLLPGQLMDISQFRDANKDTLVAGNIPATARPVILGITKAALETNSFLSAASFQETTRVLTDAAIRGKNDPLVGLKENVIIGKIIPAGTGMSAYRNIKPKEVSVAAYSIKDIEAKLKEEDKQN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LN887507
EMBL· GenBank· DDBJ
CUR40015.1
EMBL· GenBank· DDBJ
Genomic DNA
JOSX01000011
EMBL· GenBank· DDBJ
KEK15885.1
EMBL· GenBank· DDBJ
Genomic DNA
JAFFPO010000032
EMBL· GenBank· DDBJ
MCH5358040.1
EMBL· GenBank· DDBJ
Genomic DNA
WJND01000001
EMBL· GenBank· DDBJ
MRG88452.1
EMBL· GenBank· DDBJ
Genomic DNA
WJNC01000005
EMBL· GenBank· DDBJ
MRI07585.1
EMBL· GenBank· DDBJ
Genomic DNA
MCNS01000012
EMBL· GenBank· DDBJ
OCX47219.1
EMBL· GenBank· DDBJ
Genomic DNA
NFHN01000009
EMBL· GenBank· DDBJ
OUN49174.1
EMBL· GenBank· DDBJ
Genomic DNA
NFKV01000011
EMBL· GenBank· DDBJ
OUP89288.1
EMBL· GenBank· DDBJ
Genomic DNA
QAZN01000011
EMBL· GenBank· DDBJ
PTV03670.1
EMBL· GenBank· DDBJ
Genomic DNA
CP041676
EMBL· GenBank· DDBJ
QDR71998.1
EMBL· GenBank· DDBJ
Genomic DNA
CP059275
EMBL· GenBank· DDBJ
QLQ62699.1
EMBL· GenBank· DDBJ
Genomic DNA
PTLS01000022
EMBL· GenBank· DDBJ
RMX25764.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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