A0A072ZEC1 · A0A072ZEC1_PSEAI

  • Protein
    Fluoride-specific ion channel FluC
  • Gene
    crcB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

1127102030405060708090100110120
TypeIDPosition(s)Description
Binding site75Na+ (UniProtKB | ChEBI); structural
Binding site78Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC

Gene names

    • Name
      crcB
    • Synonyms
      fluC
    • ORF names
      CAZ10_21410
      , GNQ48_11110
      , GUL26_13200
      , L4V69_29880
      , PAERUG_P19_London_7_VIM_2_05_10_00281

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • P19_London_7_VIM_2_05_10
    • S567_C10_BS
    • PA221
    • VNMU148
    • 2021CK-01020
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A072ZEC1
  • Secondary accessions
    • A0A1S1C5Z5

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane33-55Helical
Transmembrane67-91Helical
Transmembrane97-119Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    127
  • Mass (Da)
    13,261
  • Last updated
    2014-10-01 v1
  • MD5 Checksum
    9D2948CB61D1FF78F66B0CADE758A56D
MWKSILAIALGAALGALLRWFLGLKLNSLLPSIPPGTLLANLVGGYVIGAAIAYFAQAPGIAPEWRLLIITGFCGGLTTFSTFSAEVVSLLQEGRLGWAAGAIATHVSGSLLMTLLGLFSMNWMLGK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CVVU01000011
EMBL· GenBank· DDBJ
CRN92510.1
EMBL· GenBank· DDBJ
Genomic DNA
WOAD01000007
EMBL· GenBank· DDBJ
MUI35558.1
EMBL· GenBank· DDBJ
Genomic DNA
WXZT01000009
EMBL· GenBank· DDBJ
MZZ13207.1
EMBL· GenBank· DDBJ
Genomic DNA
NFFZ01000011
EMBL· GenBank· DDBJ
OTI59412.1
EMBL· GenBank· DDBJ
Genomic DNA
CP136986
EMBL· GenBank· DDBJ
WOS76663.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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