A0A072UNN4 · A0A072UNN4_MEDTR

Function

Catalytic activity

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine.
    EC:2.3.2.26 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; protein ubiquitination.

Features

Showing features for active site.

137585001,0001,5002,0002,5003,0003,500
TypeIDPosition(s)Description
Active site3725Glycyl thioester intermediate

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functionubiquitin protein ligase activity
Biological Processprotein polyubiquitination
Biological Processubiquitin-dependent protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    HECT-type E3 ubiquitin transferase
  • EC number

Gene names

    • Name
      25493428
    • Ordered locus names
      MTR_4g094708

Organism names

  • Taxonomic identifier
  • Strains
    • A17
    • cv. Jemalong A17
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fabales > Fabaceae > Papilionoideae > 50 kb inversion clade > NPAAA clade > Hologalegina > IRL clade > Trifolieae > Medicago

Accessions

  • Primary accession
    A0A072UNN4

Proteomes

Subcellular Location

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, domain, compositional bias.

Type
IDPosition(s)Description
Region717-741Disordered
Region907-937Disordered
Domain1294-1335UBA
Region2027-2050Disordered
Compositional bias2030-2044Basic and acidic residues
Compositional bias2079-2108Basic and acidic residues
Region2079-2111Disordered
Region2149-2218Disordered
Compositional bias2150-2185Acidic residues
Compositional bias2198-2218Acidic residues
Region2430-2459Disordered
Region2639-2664Disordered
Domain3417-3758HECT

Sequence similarities

Belongs to the UPL family. TOM1/PTR1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    3,758
  • Mass (Da)
    415,016
  • Last updated
    2014-10-01 v1
  • MD5 Checksum
    33BC9479F5FE8AE306C5DE2D15D2B04B
MKLKRKRALEVPQKIRCFINRVAAVPLENIQEPLKDFTWEFDKGDFHHWVDLFNHFDSFFEKYIKPRKDLQIDDNFLDSDPPFPREAVLQILRVIRIILDNCANKHFYGSYEQHLSSLLASTDPDVVEATLDTLATFLKKTIGKYSIRDASLNSKLFVLAQGWGGKEEGLGLIASAVPNRCDPIAHELGCAFHFEFYAVNESDSDIKGAEPLVEGLQIIHLSDVHKCVETDLGLLHKLVREYKVPSSLRFSLLTRLRFARAFGSFSSRQQYTCIRLYAFIVLIQVCGADDLVSFFNAEPGFINELVSLLSYEDAVLEKIRVLCLHSLTALCQDRSRQPSVLTALTSGGHRGILSSLMQKSIDFVISDTSKWSVHFVEALLSLVTVLVSSSSGCSAMREAGFIPTLLPLLKDINPQHLHLVEKAVRILEAFMDYSNPAAALFRDLGGLDDTISRLKIEVSHVENGGKQPDENSESSRSAHMVGGSSVWLDDMQPLYTEPLISYHRKLLMKALLRAISLGTYAPGNTTRIYGSEENVLPQCLCIIFRRSKDFGGGVFSLAATVLSDLVQKDPTCFPVLDAAGLPSAFLDAIIDDVLNSSEAITCIPQCLDALCLNSNGLQAVKDRNSLRCFVKVFTSRTYLRALTGETLASLSSGLDELMRHAASLRGPGVDMLVEILETISKIGSAIYSSSFCHDPCSSTSAPMEMDGRDKNLILADRKESSKPDDTEQIDEPSPDASTMNTESFLPDCVNNVARLLETVLQNADTCRIFVEKKGIEAILQLFTLPLMPPSVSVGQSISAAFKNFSPQHYVSLARALCSFLREHLKSTNEILDSVGGTQLTLVESAKQSKVLKYLSSLEGILALSVFLLKATTAVVSELSTSDADVLKDIGRAYKEIIWQISLCDDSKTDEKKNNDQEPVISQAPSSTVFERESEDDTNMQTVRYTNPVFGRTGSRPLWSGGRDFVSVVRSEEGLHRRTRQGIARMRGGRTARRLEALNIDFESSSCVLEASFSQDLKKKSPDVLALEILNKLASTMRSFFTALVKGFTSPRRRADSGSLSTASKALGTVLATNFLEALSFSGHSTCAKLETSLSVKCRYLGKVVDDIAALTFDNRRRSCYTAMVNNFYVHGTFKELLTTYEATSQLLWTLPYTYPSSDIDLGKKGGANMSHYTWLLYTLQSYCRLLEYFVNSSLLLSPTSASQTELLVQPVAVGLSIGLFPVPRDPEVFVRMLQSQVLDVILPVWNHPMFYTCSPGFITSIISLVTHVYSGVGDVKRIRNNILGSTNQRFMPPPPDEATIATIVEMGFSRARAEEALRRVETNSVEMAMEWLFSHADDPIQEDDELAQALALSLGSSSETTKVDNVEKTIDVPIEEGHTKKPPVDDILAASVKLFQSSDSVAFQLSDLLVTLCNQNKGEDRPKVISYLLQQLKLCPLDFSTENCALGILAHVISLLLFEDGSTREVAAQNGIISTIIDILTNLKDKPEMGKELPVSKCISALLLILDQMLQSRPKTENIEAGTRTGSMPDSSGEHGSLQFTDTVAQEEKKIDGREKEPGMDFENVLGKPTGFATIDESHKLLDITCDLIKQHVPAVVMQAVLQLCARLTKTHALALKFLENGGLAALFSLPRKSFFPGYDTVVSAIVRHLLEDPQTLQSAMELEIRQTLSGNRHSGRVSPRSFLTSLAPVISRDPIVFMKATAAICQLETSGGRTIVVLSKEKEKEKSKSSSTEVTNECLRISESKSHDGSGKCLKSHKKVPVNLTQVIDQLLEIVLKYPPMEGQGDSKCDSNLMDIDEPTMKVKGKSKVEETVILKPESEKSAELVKVTFVLKLLSDILLMYGHAVGVILRRDSEMCQFRGSNQPSGNNGIIHHVLHRLLPFSVEESAGTDDWRGKLSEKASWFLVVLCGRSGEGRKRVTNELVKEMMSLSNFESNSLKSSLSPDKRLFTFVDLVYSILSKNSSSGSLPGSGYSPDIAKSLIDGGIIRCLTSILQVVDLDHPDAPKFATLVLKGLECLSRAANASERTFKSDGAEKRTSTSLNERPDDQMAAPSVFETEAHDQNVSSQEALRETIDNAHHQRTSQSDHHADNSNQSGEQDMRVEEEEVLAQNPPVVEMDFMREELGEGGVLHNPEQIEMAFHVENRVDDDMGDEDDGMGDDRDDGDDDEDDDDDGEDEDEDIAEGGGGMMSMADTDVEDHDDADTGDEYNNEMIDEDDDDFHENRVIEVRWREALDGLDHLQILGQHRTAGGLIDLSAEPFEGVNVDDLFRLQSFERRRQTGRSSFERPASEINGFQHPLFVRPPQSGDFVSMWSSGGNSASRDSETLSSGNLDVSHFYMFDAPTLPHDHTPSNLFGDHLGSVAPPPLTDYSLGMGSLHLPGRRVLGNGRWTDDGQPQGGAQAAAIAQAVEGQFLARMGTIAPASSPTIRQVHNSEKQEKQSDAALPSHDDPSLNVGADSTYQQFAGQEQENVAQQINLSVEGAPCEEEINVGSSVQDTGEGLQNNEPMSVQPLSLEIMPNGLDCTVNEINVTPRDNVAIPQEFVNSSIESGADVLTNNQNVAIVPMVCDGTSNVDRQPTNLELPGSGFETSNPSDCPASSIYASVDVDMGGVDAEGNQSEEPIVFEDRRDELLSTQNTEVAPDDTQADQTSANNEASGTSTIDPTFLEALPEDLRAEVLASQQAQSIQPPVYAPPSGEDIDPEFLAALPPEIQAEVLAQQRAQRVAQQAEGQPVDMDNASIIATFPADLREEVLLTSSEAVLSALPSTLLAEAQILRDRAMSHYQARSLFGSSHRLSNRRNGLGFVRRTVMDRGVGVTIDRRSALTDTLKVKEIEGEPLLNENALQALIRLLRLAQPLGKGILQRLLLNLCAHSVTRAILIYLLLDMIKPEAEGSVSRAVTLNSQRLYGCHSNTVYGRSQLWDGLPPLVFRRVLEILTYLATNHSAVAKMLFHFDQSIADSSNSSMTHMNGKGKEKVIEEGPSPKSSKTLAEAVPLVFFMKLLNKPLFLRSTAHLEQVMGLIQVVVDIAAAKLESQSQSEKAIADTQNLSVGEAEKDPPLVELDSNQLDKHDYTKSCHSNVKKNNDMYNIFLQLPQSDLRNVCSLLGREGLPDKMYKLAGEVLNKLAIIVPSHRKFFILELSESSHALTGSAVSELVTLQQTNMLGLSAGSMAGAAILRVLQALSSLISLNTSGSMDMRSDADIDQHDDKAIIWNLNTALEPLWQELSNCISAAEMQLGQSSFCPNMSNINVAENLHGSLTSPPLPPGTQRLLPFIEAFFVLCEKLQSNESIMQQDHINATAREVKESAGCSASMSGKFCGDSQRKLDGAVTFTRFAEKHRRLANAFIRQNPGLLEKSLAMMLKAPRLIDFDNKRAYFRSRIRQQHDHQLSGPLRISVRRAYILEDSYNQLRMRPTQDLKSRLNVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNNATFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWMLENDVSDIPDLTFSMDADEEKLILYEKNEVTDYELKPGGRNIRVTEETKHEYVDLVAEHLLTNAIRPQINSFLEGFNEMVPRELISIFNDKELELLISGLPEIDLDDLKANTEYTGYTVASNVVQWFWEVVKSFNKEDMARLLQFVTGTSKVPLEGFKALQGISGPQKFQIHKAYGAPDRLPSAHTCFNQLDLPEYTSKEQLQDRLLLAIHEASEGFGFG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias2030-2044Basic and acidic residues
Compositional bias2079-2108Basic and acidic residues
Compositional bias2150-2185Acidic residues
Compositional bias2198-2218Acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM001220
EMBL· GenBank· DDBJ
KEH31409.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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