A0A068WV30 · A0A068WV30_ECHGR
- ProteinSerine/threonine-protein kinase PLK4
- GeneEGR_08557
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids781 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | centriole | |
Cellular Component | centrosome | |
Cellular Component | cytoplasm | |
Cellular Component | kinetochore | |
Cellular Component | nucleus | |
Cellular Component | spindle pole | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | mitotic spindle organization |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein kinase PLK4
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Spiralia > Lophotrochozoa > Platyhelminthes > Cestoda > Eucestoda > Cyclophyllidea > Taeniidae > Echinococcus > Echinococcus granulosus group
Accessions
- Primary accessionA0A068WV30
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 17-268 | Protein kinase | ||||
Sequence: FQVFELLGRGGFAQVYRAKSVITGQEVAIKMIDKKYMHQHGLTHRVQREVEIHSRLKHPAVLELYTCFEDANYVYLVLEFCDNGELQAYIRQNGSVSEDMARHYMKQIISGLLYLHSHNILHRDLTLANLLLTKDMKVKIADFGLATKIEPGEDHTTMCGTPNYISPEVASRGHQVLETDVWSLGCMLYTLVVGHPPFDTREVRSTLSRVIAGDYEMPEHLSPDCSDLIAKLLRKQPQDRIKLSDMIRHPFI | ||||||
Region | 269-407 | Disordered | ||||
Sequence: TRSTTPRRKMEHSRDSGIDSMSRTPTIGMQSNSLTATTTTTASTANSRHSLPYRPGASILPPRPASRLSVDMHRSTQNQQSGHQTPLTPFDSRGHQPPTSATRLRGGSLQHLLPPSKSMSGLSLATSSPSPCRSASVGN | ||||||
Compositional bias | 272-286 | Basic and acidic residues | ||||
Sequence: TTPRRKMEHSRDSGI | ||||||
Compositional bias | 287-319 | Polar residues | ||||
Sequence: DSMSRTPTIGMQSNSLTATTTTTASTANSRHSL | ||||||
Compositional bias | 338-374 | Polar residues | ||||
Sequence: VDMHRSTQNQQSGHQTPLTPFDSRGHQPPTSATRLRG | ||||||
Compositional bias | 381-407 | Polar residues | ||||
Sequence: LPPSKSMSGLSLATSSPSPCRSASVGN | ||||||
Domain | 412-529 | Cryptic POLO box 1 (CPB1) | ||||
Sequence: SHQPRLSPLCTCRLRPMRTVTRMAVINILPDESVCLEFFDPQVDQQKLVVEVMGISADGQEVIIYHPNGGRGVPPNTNSPVAARSGDTYGVYRLAQLPEKYWKKYQFVSKFINMAKAH | ||||||
Domain | 530-654 | Cryptic POLO box 2 (CPB2) | ||||
Sequence: TPKVTLYTSRAKCILMEKVEPQADFEMEVLTDGSRVICLGGEATGTVQVITQTNGTVTVDRKQPLDNLPTTTRELISYAERCRRRCLEVESSLEKFNVALSPLDAEVSSPFPVIIGRRSCAASKT | ||||||
Domain | 684-775 | POLO box | ||||
Sequence: FSRHYDPVFVPSVGWVSQPSPEELQVQFNDGARLVVVYSTATVHSIRYHPPAIAGEEEEEQVYSTASSSTPLPAEVRSRLEVIPKVVKCLRS |
Family and domain databases
Sequence
- Sequence statusComplete
- Length781
- Mass (Da)86,629
- Last updated2014-10-01 v1
- ChecksumCB4EA74144ADC7B0
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 272-286 | Basic and acidic residues | ||||
Sequence: TTPRRKMEHSRDSGI | ||||||
Compositional bias | 287-319 | Polar residues | ||||
Sequence: DSMSRTPTIGMQSNSLTATTTTTASTANSRHSL | ||||||
Compositional bias | 338-374 | Polar residues | ||||
Sequence: VDMHRSTQNQQSGHQTPLTPFDSRGHQPPTSATRLRG | ||||||
Compositional bias | 381-407 | Polar residues | ||||
Sequence: LPPSKSMSGLSLATSSPSPCRSASVGN |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LK028584 EMBL· GenBank· DDBJ | CDS21559.1 EMBL· GenBank· DDBJ | Genomic DNA |