A0A068MVE1 · A0A068MVE1_SYNY4
- ProteintRNA-dihydrouridine synthase
- Genedus
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids348 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
Catalytic activity
- a 5,6-dihydrouridine in tRNA + NAD+ = a uridine in tRNA + NADH + H+
- a 5,6-dihydrouridine in tRNA + NADP+ = a uridine in tRNA + NADPH + H+
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 98 | FMN (UniProtKB | ChEBI) | |||
Active site | 128 | Proton donor | |||
Binding site | 167 | FMN (UniProtKB | ChEBI) | |||
Binding site | 197 | FMN (UniProtKB | ChEBI) | |||
Binding site | 252-253 | FMN (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | RNA binding | |
Molecular Function | tRNA dihydrouridine synthase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA-dihydrouridine synthase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Synechococcales > Merismopediaceae > Synechocystis
Accessions
- Primary accessionA0A068MVE1
Proteomes
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length348
- Mass (Da)38,427
- Last updated2014-10-01 v1
- MD5 Checksum226802B4C7A6E67CB78EA1117A49F481
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP007542 EMBL· GenBank· DDBJ | AIE73148.1 EMBL· GenBank· DDBJ | Genomic DNA |