A0A067QF62 · A0A067QF62_ZOONE

Function

function

Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentDUBm complex
Cellular ComponentSAGA complex
Molecular Functiontranscription coactivator activity
Molecular Functionzinc ion binding
Biological Processchromatin organization
Biological Processregulation of transcription by RNA polymerase II

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    SAGA-associated factor 11 homolog

Gene names

    • Name
      Sgf11
    • ORF names
      L798_04470

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Polyneoptera > Dictyoptera > Blattodea > Blattoidea > Termitoidae > Termopsidae > Zootermopsis

Accessions

  • Primary accession
    A0A067QF62

Proteomes

Subcellular Location

Keywords

  • Cellular component

Interaction

Subunit

Component of some SAGA transcription coactivator-HAT complexes. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).

Protein-protein interaction databases

Family & Domains

Features

Showing features for zinc finger, region, domain, compositional bias.

TypeIDPosition(s)Description
Zinc finger94-115SGF11-type
Region139-182Disordered
Domain208-276SCA7
Region276-345Disordered
Compositional bias277-291Basic and acidic residues
Compositional bias292-312Polar residues
Compositional bias328-345Polar residues

Domain

The C-terminal SGF11-type zinc-finger domain forms part of the 'catalytic lobe' of the SAGA deubiquitination module.
The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

Sequence similarities

Belongs to the SGF11 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    345
  • Mass (Da)
    38,500
  • Last updated
    2014-09-03 v1
  • Checksum
    F78FB6FAB1CC028F
MATTEEKEMELIRQFKLYMSNPENVILAANSVFEKLVDDVILGVVFEVHHAAKAGLFDLEDGLQEEKTNCEIVDGTDVDIFGQQPIKKAQECICYCPTCKHSLAASRFAPHLAKCMGMGRNSSRIASRRIANNSKESVAYSGMMSDDEDDADWTATPDRRRKKRDRNGTRRSKNQKTVRNGDVTVENNVSTEISSSNINSSNMNYDGMTYEEKKTLLMQICGVISEHTRRLCTRSMRCPQHSDDQRRAVRASLLGSQISDVNATPDIIQVDVDTYEEGDSQSMRESLGRSWEQEHSNTSSPADSASTSSSSSKKREKLPKSKSKNSTKGHKSSPNFSNNHHSQGD

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias277-291Basic and acidic residues
Compositional bias292-312Polar residues
Compositional bias328-345Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KK853628
EMBL· GenBank· DDBJ
KDR03827.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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