A0A067HDL0 · A0A067HDL0_ECOLX
- ProteintRNA-specific adenosine deaminase
- GenetadA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids167 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
Catalytic activity
- adenosine34 in tRNA + H+ + H2O = inosine34 in tRNA + NH4+
RHEA-COMP:10373 CHEBI:74411 Position: 34+ CHEBI:15378 + CHEBI:15377 = RHEA-COMP:10374 CHEBI:82852 Position: 34+ CHEBI:28938
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | tRNA-specific adenosine-34 deaminase activity | |
Molecular Function | zinc ion binding | |
Biological Process | tRNA wobble adenosine to inosine editing |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA-specific adenosine deaminase
- EC number
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia
Accessions
- Primary accessionA0A067HDL0
Proteomes
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 6-117 | CMP/dCMP-type deaminase | ||||
Sequence: FSHEYWMRHAMTLAKRAWDEREVPVGAVLVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTLEPCVMCAGAMIHSRIGRVVFGARDAKTGAAGSL |
Sequence similarities
Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length167
- Mass (Da)18,736
- Last updated2014-09-03 v1
- ChecksumD5BF3454A86874AD
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP023197 EMBL· GenBank· DDBJ | BCG35976.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CAUZHL010000004 EMBL· GenBank· DDBJ | CAK1212037.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BGDN01000029 EMBL· GenBank· DDBJ | GDP61171.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
UFXW01000004 EMBL· GenBank· DDBJ | STC81838.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
UFZD01000005 EMBL· GenBank· DDBJ | STE11783.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
UGAB01000002 EMBL· GenBank· DDBJ | STF40850.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
UGBW01000003 EMBL· GenBank· DDBJ | STH81448.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
UGCV01000008 EMBL· GenBank· DDBJ | STJ20068.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
UGEM01000003 EMBL· GenBank· DDBJ | STL19653.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
UGEM01000004 EMBL· GenBank· DDBJ | STP18482.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CAADIS010000004 EMBL· GenBank· DDBJ | VFS16718.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CABEEY010000003 EMBL· GenBank· DDBJ | VTR15259.1 EMBL· GenBank· DDBJ | Genomic DNA |