A0A067HDL0 · A0A067HDL0_ECOLX

  • Protein
    tRNA-specific adenosine deaminase
  • Gene
    tadA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

116720406080100120140160
TypeIDPosition(s)Description
Binding site57Zn2+ (UniProtKB | ChEBI); catalytic
Active site59Proton donor
Binding site87Zn2+ (UniProtKB | ChEBI); catalytic
Binding site90Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Molecular FunctiontRNA-specific adenosine-34 deaminase activity
Molecular Functionzinc ion binding
Biological ProcesstRNA wobble adenosine to inosine editing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA-specific adenosine deaminase
  • EC number

Gene names

    • Name
      tadA
    • Synonyms
      tadA_1
      , tadA_2
    • ORF names
      BvCmsNSP007_00662
      , FGAF848_29730
      , NCTC10089_01291
      , NCTC10767_02565
      , NCTC7928_01421
      , NCTC8621_01375
      , NCTC8959_02488
      , NCTC9001_01557
      , NCTC9075_00133
      , NCTC9075_01944
      , NCTC9081_05625
      , TUM18780_11380

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • NS-P007
    • NCTC10767
    • NCTC7928
    • NCTC8621
    • NCTC8959
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia

Accessions

  • Primary accession
    A0A067HDL0

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-117CMP/dCMP-type deaminase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    167
  • Mass (Da)
    18,736
  • Last updated
    2014-09-03 v1
  • Checksum
    D5BF3454A86874AD
MSEVEFSHEYWMRHAMTLAKRAWDEREVPVGAVLVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTLEPCVMCAGAMIHSRIGRVVFGARDAKTGAAGSLMDVLHHPGMNHRVEITEGILADECAALLSDFFRMRRQEIKAQKKAQSSTD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP023197
EMBL· GenBank· DDBJ
BCG35976.1
EMBL· GenBank· DDBJ
Genomic DNA
CAUZHL010000004
EMBL· GenBank· DDBJ
CAK1212037.1
EMBL· GenBank· DDBJ
Genomic DNA
BGDN01000029
EMBL· GenBank· DDBJ
GDP61171.1
EMBL· GenBank· DDBJ
Genomic DNA
UFXW01000004
EMBL· GenBank· DDBJ
STC81838.1
EMBL· GenBank· DDBJ
Genomic DNA
UFZD01000005
EMBL· GenBank· DDBJ
STE11783.1
EMBL· GenBank· DDBJ
Genomic DNA
UGAB01000002
EMBL· GenBank· DDBJ
STF40850.1
EMBL· GenBank· DDBJ
Genomic DNA
UGBW01000003
EMBL· GenBank· DDBJ
STH81448.1
EMBL· GenBank· DDBJ
Genomic DNA
UGCV01000008
EMBL· GenBank· DDBJ
STJ20068.1
EMBL· GenBank· DDBJ
Genomic DNA
UGEM01000003
EMBL· GenBank· DDBJ
STL19653.1
EMBL· GenBank· DDBJ
Genomic DNA
UGEM01000004
EMBL· GenBank· DDBJ
STP18482.1
EMBL· GenBank· DDBJ
Genomic DNA
CAADIS010000004
EMBL· GenBank· DDBJ
VFS16718.1
EMBL· GenBank· DDBJ
Genomic DNA
CABEEY010000003
EMBL· GenBank· DDBJ
VTR15259.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp