A0A066UWL9 · A0A066UWL9_9VIBR

  • Protein
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • Gene
    bioH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Pathway

Cofactor biosynthesis; biotin biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site22substrate
Active site82Nucleophile
Binding site82-83substrate
Binding site146-150substrate
Active site210
Active site238
Binding site238substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionpimelyl-[acyl-carrier protein] methyl ester esterase activity
Biological Processbiotin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • EC number
  • Alternative names
    • Biotin synthesis protein BioH
    • Carboxylesterase BioH

Gene names

    • Name
      bioH
    • ORF names
      VFDL14_15285

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Dalian14
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Vibrionales > Vibrionaceae > Vibrio

Accessions

  • Primary accession
    A0A066UWL9

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain16-244AB hydrolase-1

Sequence similarities

Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    258
  • Mass (Da)
    28,641
  • Last updated
    2014-09-03 v1
  • Checksum
    BE10130C3A0AFB20
MSDKLYWHVSGQGPDLVLVHGWGMNGAVWQQTVTALETQFRVHVVDLPGYGHSSHCHADALEGIAEQLMEEAPKQAIWVGWSLGGLVATHMALHHTDYVSKLVTVASSPKFAAAKEPVLWRGIQPNVLTNFTEQLVEDFQTTIERFMALQAMGSPSARQDVKQLKQAVLSRPLPNPDSLLAGLKMLSDVDLRERLPELKVPMLRLYGRLDGLVPIKVAKDLEKALPNTEQYIFTQSSHAPFMTEADAFCCELISFAEK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JFFR01000018
EMBL· GenBank· DDBJ
KDN28579.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp