A0A066URR1 · A0A066URR1_9VIBR

  • Protein
    Phosphoheptose isomerase
  • Gene
    gmhA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.

Miscellaneous

The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site49-51substrate
Binding site91-92substrate
Binding site117-119substrate
Binding site122substrate
Binding site172Zn2+ (UniProtKB | ChEBI)
Binding site172substrate
Binding site180Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncarbohydrate derivative binding
Molecular FunctionD-sedoheptulose 7-phosphate isomerase activity
Molecular Functionzinc ion binding
Biological Processcarbohydrate metabolic process
Biological ProcessD-glycero-D-manno-heptose 7-phosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoheptose isomerase
  • EC number
  • Alternative names
    • Sedoheptulose 7-phosphate isomerase

Gene names

    • Name
      gmhA
    • ORF names
      F2P58_15505
      , F2Z80_12180
      , VFDL14_09175

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • Dalian14
    • S7-72
    • AN60
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Vibrionales > Vibrionaceae > Vibrio

Accessions

  • Primary accession
    A0A066URR1

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homotetramer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain34-196SIS

Sequence similarities

Belongs to the SIS family. GmhA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    196
  • Mass (Da)
    21,140
  • Last updated
    2014-09-03 v1
  • Checksum
    BC45A810F37CC269
MLDSIKESFTESIQIQIAAAEALPDAITHAAQAMVATLLNGNKILCCGNGGSASNAQQFVSCLLNRFETERPSLPAMALTADNTTLTAVANDYHYEEIFSKQVRAFGQTGDILLAISTSGNSKNIIKAMEAAVTRDMTIIAFTGKDGGEMAGLLGEHDVEIRIPSHRTARIHEVHMVTLHCLCDLIDQVLFPAHEE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VWSE01000008
EMBL· GenBank· DDBJ
KAB0286135.1
EMBL· GenBank· DDBJ
Genomic DNA
VXDD01000001
EMBL· GenBank· DDBJ
KAB0304631.1
EMBL· GenBank· DDBJ
Genomic DNA
JFFR01000028
EMBL· GenBank· DDBJ
KDN26829.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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