A0A062WPD2 · A0A062WPD2_9ACTN

  • Protein
    Glycerol kinase
  • Gene
    glpK
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site17ADP (UniProtKB | ChEBI)
Binding site17ATP (UniProtKB | ChEBI)
Binding site17sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site18ATP (UniProtKB | ChEBI)
Binding site87glycerol (UniProtKB | ChEBI)
Binding site87sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site88glycerol (UniProtKB | ChEBI)
Binding site88sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site139glycerol (UniProtKB | ChEBI)
Binding site139sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site249glycerol (UniProtKB | ChEBI)
Binding site249sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site250glycerol (UniProtKB | ChEBI)
Binding site271ADP (UniProtKB | ChEBI)
Binding site271ATP (UniProtKB | ChEBI)
Binding site315ADP (UniProtKB | ChEBI)
Binding site315ATP (UniProtKB | ChEBI)
Binding site415ADP (UniProtKB | ChEBI)
Binding site415ATP (UniProtKB | ChEBI)
Binding site419ADP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol-3-phosphate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • ORF names
      BMG523Draft_03247

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BMG5.23
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Frankiales > Frankiaceae > Frankia

Accessions

  • Primary accession
    A0A062WPD2

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-255Carbohydrate kinase FGGY N-terminal
Domain266-454Carbohydrate kinase FGGY C-terminal

Sequence similarities

Belongs to the FGGY kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    510
  • Mass (Da)
    54,510
  • Last updated
    2014-09-03 v1
  • Checksum
    19929EB83B4B6D0A
MSVPARGSLVAAVDQGTTGTTVCLLDRDGVVVGRGYTGIRPGFPRPGWVEQDPDELWRSVVDTVAAALAGCGRRAGELAALGITNQRETTVLWDRRTSAPVHPAIGWQDRRTAAVCERLTAEGHAGAVGERTGLVLDPYFSGTKIGWILDDDPGLRRRAGRGEIAFGTVDSWLVWKLTAGAAHVTDVTNASRTLLLDLAAATWSPEMLDLLGVPAEVLPAVAPSSRVYAETDPDAFLGVRIPVAAVIGDQQAALFAQGCFEPGQAKNTYGTGSFVLVNTGSALPAPQSTLLRTAAFQLDGEPVRYALEGAVLSTGAAVDWLRDSLGIIRDATETADLAASLTGNDGVYFVPALAGLGAPHWDPRARGALLGITRGTTRAHVVRAVLEGIAYRTRDVVEAMGAAGFPVRELRADGGAARNHWLMQFQADLLGVELDVPDNIETTALGSAYLAGLATGFFADREELAGHRRSAERYRPRLSRAERDRSYRRWLRAVDRARDWAKDADDADWD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JDWE01000034
EMBL· GenBank· DDBJ
KDA41947.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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