A0A061IMF4 · A0A061IMF4_CRIGR
- ProteinRas-related protein Rab-8A
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids555 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- GTP + H2O = GDP + H+ + phosphateThis reaction proceeds in the forward direction.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | centriole | |
Cellular Component | cilium | |
Cellular Component | dendritic spine | |
Cellular Component | Golgi apparatus | |
Cellular Component | midbody | |
Cellular Component | phagocytic vesicle membrane | |
Cellular Component | plasma membrane | |
Cellular Component | recycling endosome membrane | |
Cellular Component | synaptic vesicle | |
Cellular Component | trans-Golgi network transport vesicle | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Biological Process | cilium assembly | |
Biological Process | endocytic recycling | |
Biological Process | Golgi vesicle fusion to target membrane | |
Biological Process | neurotransmitter receptor transport to postsynaptic membrane | |
Biological Process | protein localization to plasma membrane | |
Biological Process | protein secretion | |
Biological Process | regulation of exocytosis | |
Biological Process | signal transduction | |
Biological Process | vesicle docking involved in exocytosis |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRas-related protein Rab-8A
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Cricetidae > Cricetinae > Cricetulus
Accessions
- Primary accessionA0A061IMF4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Lipid-anchor
Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 253-344 | SH2 | ||||
Sequence: WFHGTISREVAENLLESQPLGTFLIRVSHSHVGYTLSYKAQTCCRHFMVKLSDDGTFILAGDHVTHASLDALVTFHQQKPIRPYRELLTQAC | ||||||
Region | 368-411 | Disordered | ||||
Sequence: AESRGPTEVQRPSSCPPEEAPERRPNAATDGKLPSAPCSPKAHF | ||||||
Region | 461-500 | Disordered | ||||
Sequence: RVSSWDSASHSKDPGAATSLQNLSEPQAQRSRESTFTASR | ||||||
Region | 523-555 | Disordered | ||||
Sequence: SVQATKSEPEDLPEAQDWLPEEYLRPPPFAPGY |
Sequence similarities
Belongs to the small GTPase superfamily. Rab family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length555
- Mass (Da)62,398
- Last updated2014-09-03 v1
- Checksum7D37137B23295FE7