A0A061HMZ3 · A0A061HMZ3_BLUGR

Function

function

ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2.
RNA helicase.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleolus
Cellular Componentsmall-subunit processome
Molecular FunctionATP binding
Molecular Functionhydrolase activity
Molecular Functionidentical protein binding
Molecular FunctionRNA binding
Molecular FunctionRNA helicase activity
Biological ProcessrRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent RNA helicase
  • EC number

Gene names

    • ORF names
      BGT96224_1464
      , BGT96224V2_LOCUS3366

Organism names

Accessions

  • Primary accession
    A0A061HMZ3

Proteomes

Subcellular Location

Interaction

Subunit

Interacts with the U3 and U14 snoRNAs. Associates with pre-ribosomal complexes.

Family & Domains

Features

Showing features for region, domain, motif, compositional bias.

TypeIDPosition(s)Description
Region1-36Disordered
Domain49-77DEAD-box RNA helicase Q
Motif49-77Q motif
Domain80-254Helicase ATP-binding
Domain280-439Helicase C-terminal
Region689-722Disordered
Region737-767Disordered
Compositional bias746-767Basic and acidic residues

Domain

The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

Sequence similarities

Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    797
  • Mass (Da)
    89,858
  • Last updated
    2014-09-03 v1
  • Checksum
    1088C1ED1A904E9E
MTSGTKDRKSKPLGKSKGESRNLKRKREDEEHGSLQQAVEKLDATTVIKDFSDLPLCQATRSGLESSHFKTLTDIQCKAIPLALKGKDILGAARTGSGKTLAFLIPVLDNLYRQKWTELDGLGALIISPTRELAIQIFEVLRKIGRNHSFSAGLVIGGRNLQEERERLGRMNILVCTPGRMLQHMDQTAAFEVGNLQMLVLDEADRILDMGFKHSIDAIIEHLPKQRQTLLFSATQTKKVSDLARLSLKDPEYVAVHEAALSATPATLQQYYVETKLPEKLNTLFSFIRSNLKAKIIVFLSSGKQVRFVYESFRRLQPGIPLLHLHGRQKQTARLDITARFSASQNSCIFATDVVARGLDFPAVDWVIQLDCPEDSDTYIHRVGRTARYERAGKAVMFLDPSEVEGMLKRLENKKVPILRTKPRDNKQQRIDSQFQNMCFQDPELKYLAQKAFTSYAKSLYLQKDKEVFKLDEYDLEGFASSLGLPGAPKIKFQKGEDARKIKNAPRATFSNDEEIEALGDTIVSGKEKVRTKYDRMFERRNQDVLSGHYSKMISHNDGDDASLAMLGDADEDNDFLSVKRVIPVDIDGSTFHEDQESTGPAPKIVSGLGTEPIVVDSKRKEKLLKSKKKLTKLKEKGTKLVYDDDGNPHQVYELEDEEGFHQRGPAEVQRAKFVESEVARIQEADVHDKELAKQKKREKRDKKKAREAAGIIEDESEEEVPDLMEADGDEALKLLASLPLSSSKEDGRPTKRPRKWFEDDSDAEQKAQARNLDIEIPDETNTLEDLETYAAAILNE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias746-767Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KE375048
EMBL· GenBank· DDBJ
EPQ64915.1
EMBL· GenBank· DDBJ
Genomic DNA
UIGY01000076
EMBL· GenBank· DDBJ
SUZ10221.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp