A0A061CZ15 · A0A061CZ15_PSEOL

Function

function

Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site10-15ATP (UniProtKB | ChEBI)
Binding site31AMP (UniProtKB | ChEBI)
Binding site36AMP (UniProtKB | ChEBI)
Binding site57-59AMP (UniProtKB | ChEBI)
Binding site85-88AMP (UniProtKB | ChEBI)
Binding site92AMP (UniProtKB | ChEBI)
Binding site123ATP (UniProtKB | ChEBI)
Binding site132-133ATP (UniProtKB | ChEBI)
Binding site156AMP (UniProtKB | ChEBI)
Binding site167AMP (UniProtKB | ChEBI)
Binding site201ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionadenylate kinase activity
Molecular FunctionATP binding
Biological ProcessAMP salvage

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenylate kinase
  • EC number
  • Short names
    AK
  • Alternative names
    • ATP-AMP transphosphorylase
    • ATP:AMP phosphotransferase
    • Adenylate monophosphate kinase

Gene names

    • Name
      adk
    • ORF names
      C5L43_01430
      , EGJ44_06545
      , N5J11_02335
      , N7581_08105
      , NCTC10692_00439
      , NCTC10860_01403

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • YKJ
    • NCTC10692
    • NCTC10860
    • PO_271
    • GD03704
    • GD04039
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas > Pseudomonas oleovorans/pseudoalcaligenes group

Accessions

  • Primary accession
    A0A061CZ15
  • Secondary accessions
    • A0A379JPB7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region30-59NMP
Region122-159LID
Domain123-158Adenylate kinase active site lid

Domain

Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.

Sequence similarities

Belongs to the adenylate kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    215
  • Mass (Da)
    23,245
  • Last updated
    2014-09-03 v1
  • Checksum
    2855DFA2611695B9
MRVILLGAPGAGKGTQARYITEKFGIPQISTGDMLRAAVKAGTELGLKAKSVMDAGGLVSDDLIINLVKERIAQADCANGFLFDGFPRTIPQAEALREAGVALDHVVEIAVEDEEIVKRLSGRRVHPASGRVYHIEYNPPKVAGKDDISGEELVQREDDKEETVRHRLSVYHSQTKPLVDFYKKLSAETGTPKYSHIPGVGSVEEITAKTLAALG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAOEDG010000013
EMBL· GenBank· DDBJ
MDG9978017.1
EMBL· GenBank· DDBJ
Genomic DNA
JAOCJE010000001
EMBL· GenBank· DDBJ
MDH1338123.1
EMBL· GenBank· DDBJ
Genomic DNA
PTLV01000014
EMBL· GenBank· DDBJ
PPV42481.1
EMBL· GenBank· DDBJ
Genomic DNA
RHRS01000012
EMBL· GenBank· DDBJ
RRW37772.1
EMBL· GenBank· DDBJ
Genomic DNA
UGUV01000002
EMBL· GenBank· DDBJ
SUD50051.1
EMBL· GenBank· DDBJ
Genomic DNA
UGUW01000004
EMBL· GenBank· DDBJ
SUD59135.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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