A0A061AKR6 · A0A061AKR6_CAEEL
- Proteindual-specificity kinase
- Genembk-2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids779 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Publications for A0A061AKR6
Regulation of MBK-2/Dyrk kinase by dynamic cortical anchoring during the oocyte-to-zygote transition.
- CategoriesExpression, Interaction
- Source
Cited inMapped toThe eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegans embryo.
- CategoriesExpression, Phenotypes & Variants
- SourceWormBase: WBGene00003150, WormBase: WBGene00003150
The C. elegans DYRK Kinase MBK-2 marks oocyte proteins for degradation in response to meiotic maturation.
- AnnotationMBK-2 directly phosphorylates MEI-1 and OMA-1 in vitro and that this activity is essential for their degradation in oocytes.
- CategoriesPTM / Processing, Subcellular Location, Expression, Interaction
- Source
Fertilization initiates the transition from anaphase I to metaphase II during female meiosis in C. elegans.
- CategoriesExpression
- SourceWormBase: WBGene00003150
Coordinate activation of maternal protein degradation during the egg-to- embryo transition in C. elegans.
- AnnotationMBK-2 functions as a temporal regulator of protein stability and that coordinate activation of maternal protein degradation is one of the mechanisms that drives the transition from symmetric egg to patterned embryo.
- CategoriesFunction, Phenotypes & Variants, Expression, Phenotypes & Variants
- Source
Characterization of Caenorhabditis elegans homologs of the Down syndrome candidate gene DYRK1A.
- CategoriesExpression, Phenotypes & Variants, Phenotypes & Variants
- Source