A0A060ZSR0 · A0A060ZSR0_9ACTN
- Protein2-deoxy-scyllo-inosamine dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids342 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the oxidation of 2-deoxy-scyllo-inosamine (DOIA) with NAD+ or NADP+, forming 3-amino-2,3-dideoxy-scyllo-inosose (amino-DOI).
Catalytic activity
- 2-deoxy-scyllo-inosamine + NAD+ = 3-amino-2,3-dideoxy-scyllo-inosose + NADH + H+
Cofactor
Pathway
Antibiotic biosynthesis.
Metabolic intermediate biosynthesis; 2-deoxystreptamine biosynthesis; 2-deoxystreptamine from D-glucose 6-phosphate: step 3/4.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | oxidoreductase activity | |
Molecular Function | zinc ion binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name2-deoxy-scyllo-inosamine dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces > Streptomyces violaceusniger group
Accessions
- Primary accessionA0A060ZSR0
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 10-340 | Enoyl reductase (ER) | |||
Sequence similarities
Belongs to the zinc-containing alcohol dehydrogenase family. DOIA dehydrogenase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length342
- Mass (Da)35,722
- Last updated2014-09-03 v1
- ChecksumC30C0B7D9012D2B4
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LK022848 EMBL· GenBank· DDBJ | CDR06436.1 EMBL· GenBank· DDBJ | Genomic DNA |