A0A060XQP6 · OMM64_ONCMY
- ProteinOtolith matrix protein OMM-64
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids628 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
Calcium-binding component of otoliths, a calcium carbonate structure of the inner ear involved in hearing and balance sensing (PubMed:18410381).
Binds calcium (PubMed:18410381, PubMed:28866388).
Binds calcium (PubMed:18410381, PubMed:28866388).
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | extracellular region |
Names & Taxonomy
Protein names
- Recommended nameOtolith matrix protein OMM-64
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Protacanthopterygii > Salmoniformes > Salmonidae > Salmoninae > Oncorhynchus
Accessions
- Primary accessionA0A060XQP6
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Note: Accumulates in the ring-like structures of otoliths.
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-20 | |||||
Sequence: MLSRLLIVPLIFALAGLAIS | ||||||
Chain | PRO_5001591264 | 21-628 | Otolith matrix protein OMM-64 | |||
Sequence: APVNDGTEADNDERAASLLVHLKGDKDGGGLTGSPDGVSAGTTDGTDSSKELAGGAVDSSPDTTDTPDASSSDIFPDTNNRDTSVETTGNPDDSDAPDAAESAGSQDTTDAADASEAVAETVDTYDIPDTDGADDREKVSTEVSTEDLDSAGVDKSPESDSTESPGSDSAESPGSDSAESPGSDSTESPGSDSTESPRSDSTDEVLTDVQADSADVTSDDMDEATETDKDDDKSDDKSDADAATDKDDSDEDKDTELDGKAHAEDTQTEEAADSDSKQGAADSDSDTDDDRPEKDVKNDSDDSKDTTEDDKPDKDDKKNRDSADNSNDDSDEMIQVPREELEQQEINLKEGGVIGSQEETVASDMEEGSDVGDQKPGPEDSIEEGSPVGRQDFKHPQDSEEEELEKEAKKEKELEEAEEERTLKTIESDSQEDSVDESEAEPDSNSKKDIGTSDAPEPQEDDSEEDTDDSMMKEPKDSDDAESDKDDKDKNDMDKEDMDKDDMDKDDMDKDDMDKDDVDKDASDSVDDQSESDAEPGADSHTVVDEIDGEETMTPDSEEIMKSGEMDSVVEATEVPADILDQPDQQDDMTQGASQAADAAATALAAQS | ||||||
Glycosylation | 318 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Proteomic databases
Expression
Tissue specificity
Specifically expressed in otolith matrix-producing cells.
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 43-628 | Disordered | ||||
Sequence: KGDKDGGGLTGSPDGVSAGTTDGTDSSKELAGGAVDSSPDTTDTPDASSSDIFPDTNNRDTSVETTGNPDDSDAPDAAESAGSQDTTDAADASEAVAETVDTYDIPDTDGADDREKVSTEVSTEDLDSAGVDKSPESDSTESPGSDSAESPGSDSAESPGSDSTESPGSDSTESPRSDSTDEVLTDVQADSADVTSDDMDEATETDKDDDKSDDKSDADAATDKDDSDEDKDTELDGKAHAEDTQTEEAADSDSKQGAADSDSDTDDDRPEKDVKNDSDDSKDTTEDDKPDKDDKKNRDSADNSNDDSDEMIQVPREELEQQEINLKEGGVIGSQEETVASDMEEGSDVGDQKPGPEDSIEEGSPVGRQDFKHPQDSEEEELEKEAKKEKELEEAEEERTLKTIESDSQEDSVDESEAEPDSNSKKDIGTSDAPEPQEDDSEEDTDDSMMKEPKDSDDAESDKDDKDKNDMDKEDMDKDDMDKDDMDKDDMDKDDVDKDASDSVDDQSESDAEPGADSHTVVDEIDGEETMTPDSEEIMKSGEMDSVVEATEVPADILDQPDQQDDMTQGASQAADAAATALAAQS | ||||||
Compositional bias | 79-111 | Polar residues | ||||
Sequence: SSPDTTDTPDASSSDIFPDTNNRDTSVETTGNP | ||||||
Compositional bias | 149-176 | Basic and acidic residues | ||||
Sequence: DTDGADDREKVSTEVSTEDLDSAGVDKS | ||||||
Compositional bias | 177-216 | Polar residues | ||||
Sequence: PESDSTESPGSDSAESPGSDSAESPGSDSTESPGSDSTES | ||||||
Compositional bias | 235-249 | Acidic residues | ||||
Sequence: DVTSDDMDEATETDK | ||||||
Compositional bias | 250-264 | Basic and acidic residues | ||||
Sequence: DDDKSDDKSDADAAT | ||||||
Compositional bias | 273-366 | Basic and acidic residues | ||||
Sequence: KDTELDGKAHAEDTQTEEAADSDSKQGAADSDSDTDDDRPEKDVKNDSDDSKDTTEDDKPDKDDKKNRDSADNSNDDSDEMIQVPREELEQQEI | ||||||
Compositional bias | 388-451 | Basic and acidic residues | ||||
Sequence: GSDVGDQKPGPEDSIEEGSPVGRQDFKHPQDSEEEELEKEAKKEKELEEAEEERTLKTIESDSQ | ||||||
Compositional bias | 460-475 | Basic and acidic residues | ||||
Sequence: AEPDSNSKKDIGTSDA | ||||||
Compositional bias | 489-518 | Basic and acidic residues | ||||
Sequence: DSMMKEPKDSDDAESDKDDKDKNDMDKEDM | ||||||
Compositional bias | 519-534 | Acidic residues | ||||
Sequence: DKDDMDKDDMDKDDMD | ||||||
Compositional bias | 554-568 | Basic and acidic residues | ||||
Sequence: AEPGADSHTVVDEID |
Domain
The Asp/Glu-rich (acidic) region mediates binding to calcium.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length628
- Mass (Da)66,567
- Last updated2014-09-03 v1
- Checksum9487E9C6E1E5CA20
Features
Showing features for sequence conflict, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 44 | in Ref. 1; BAG14384 | ||||
Sequence: G → A | ||||||
Compositional bias | 79-111 | Polar residues | ||||
Sequence: SSPDTTDTPDASSSDIFPDTNNRDTSVETTGNP | ||||||
Compositional bias | 149-176 | Basic and acidic residues | ||||
Sequence: DTDGADDREKVSTEVSTEDLDSAGVDKS | ||||||
Sequence conflict | 166 | in Ref. 1; BAG14384 | ||||
Sequence: E → K | ||||||
Compositional bias | 177-216 | Polar residues | ||||
Sequence: PESDSTESPGSDSAESPGSDSAESPGSDSTESPGSDSTES | ||||||
Compositional bias | 235-249 | Acidic residues | ||||
Sequence: DVTSDDMDEATETDK | ||||||
Compositional bias | 250-264 | Basic and acidic residues | ||||
Sequence: DDDKSDDKSDADAAT | ||||||
Compositional bias | 273-366 | Basic and acidic residues | ||||
Sequence: KDTELDGKAHAEDTQTEEAADSDSKQGAADSDSDTDDDRPEKDVKNDSDDSKDTTEDDKPDKDDKKNRDSADNSNDDSDEMIQVPREELEQQEI | ||||||
Sequence conflict | 369 | in Ref. 1; BAG14384 | ||||
Sequence: K → E | ||||||
Compositional bias | 388-451 | Basic and acidic residues | ||||
Sequence: GSDVGDQKPGPEDSIEEGSPVGRQDFKHPQDSEEEELEKEAKKEKELEEAEEERTLKTIESDSQ | ||||||
Compositional bias | 460-475 | Basic and acidic residues | ||||
Sequence: AEPDSNSKKDIGTSDA | ||||||
Compositional bias | 489-518 | Basic and acidic residues | ||||
Sequence: DSMMKEPKDSDDAESDKDDKDKNDMDKEDM | ||||||
Compositional bias | 519-534 | Acidic residues | ||||
Sequence: DKDDMDKDDMDKDDMD | ||||||
Compositional bias | 554-568 | Basic and acidic residues | ||||
Sequence: AEPGADSHTVVDEID |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB213022 EMBL· GenBank· DDBJ | BAG14384.1 EMBL· GenBank· DDBJ | mRNA | ||
FR905797 EMBL· GenBank· DDBJ | CDQ81607.1 EMBL· GenBank· DDBJ | Genomic DNA |