A0A060WWU8 · A0A060WWU8_ONCMY
- ProteinPhosphodiesterase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids527 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Cofactor
Note: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.
Features
Showing features for active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity | |
Molecular Function | metal ion binding | |
Biological Process | negative regulation of cAMP-mediated signaling | |
Biological Process | negative regulation of cGMP-mediated signaling | |
Biological Process | signal transduction |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphodiesterase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Protacanthopterygii > Salmoniformes > Salmonidae > Salmoninae > Oncorhynchus
Accessions
- Primary accessionA0A060WWU8
Proteomes
PTM/Processing
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 378-527 | PDEase | ||||
Sequence: YQDPRFDAEAANIPLVCELGIDKLSFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFAILTTAGFQETLTEIEILALIVGCVCHDLDHRGTNNAFQAKWVTLSVDTRTLAGTHAQAL |
Sequence similarities
Belongs to the cyclic nucleotide phosphodiesterase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length527
- Mass (Da)59,480
- Last updated2014-09-03 v1
- Checksum446A1EA3E41B5100
Keywords
- Technical term