A0A060VD92 · A0A060VD92_HUMAN

  • Protein
    ABO glycosyltransferase
  • Gene
    ABO
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 1 Mn2+ ion per subunit.

Features

Showing features for binding site, active site.

136550100150200250300350
Type
IDPosition(s)Description
Binding site111-113UDP-N-acetyl-alpha-D-galactosamine (UniProtKB | ChEBI)
Binding site116UDP-N-acetyl-alpha-D-galactosamine (UniProtKB | ChEBI)
Binding site201Mn2+ (UniProtKB | ChEBI)
Binding site201-203UDP-N-acetyl-alpha-D-galactosamine (UniProtKB | ChEBI)
Binding site203Mn2+ (UniProtKB | ChEBI)
Binding site223an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative (UniProtKB | ChEBI)
Binding site235an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative (UniProtKB | ChEBI)
Active site293Nucleophile
Binding site293an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative (UniProtKB | ChEBI)
Binding site316an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionhexosyltransferase activity
Molecular Functionmetal ion binding
Biological Processcarbohydrate metabolic process

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • ABO glycosyltransferase

Gene names

    • Name
      ABO

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A060VD92

Subcellular Location

Membrane
; Single-pass type II membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-27Helical

Keywords

  • Cellular component

PTM/Processing

Proteomic databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region345-365Disordered

Sequence similarities

Belongs to the glycosyltransferase 6 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    365
  • Mass (Da)
    42,155
  • Last updated
    2014-09-03 v1
  • Checksum
    97AA6EE6F38954C9
KPKCHALRPMILFLIMLVLVLFGYGVLSPRSLMPGSLERGFCMAVREPDHLQRVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQLAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDEDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRNRERLPGALGGLPAAPSPSRPWF

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LK022844
EMBL· GenBank· DDBJ
CDQ52058.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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