A0A060PMH1 · A0A060PMH1_9SAUR

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

134750100150200250300
TypeIDPosition(s)Description
Binding site51Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site65Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site150Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site164Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site169a ubiquinone (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      cytb

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Lepidosauria > Squamata > Bifurcata > Unidentata > Scinciformata > Scincidae > Sphenomorphinae > Scincella

Accessions

  • Primary accession
    A0A060PMH1

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane51-71Helical
Transmembrane83-102Helical
Transmembrane108-134Helical
Transmembrane146-167Helical
Transmembrane197-218Helical
Transmembrane256-276Helical
Transmembrane291-308Helical
Transmembrane315-338Helical

Keywords

Interaction

Subunit

The cytochrome bc1 complex contains 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and probably 6 low-molecular weight proteins.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-177Cytochrome b/b6 N-terminal region profile
Domain178-347Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    347
  • Mass (Da)
    38,846
  • Last updated
    2014-09-03 v1
  • Checksum
    548739BB28D35EBD
FGSLLGLCLIVQVLTGLFLAMHYTADITSAFSSVAHICRDVQYGWLIRNIHANGASMFFICLYLHIGRGLYYGSYMYKETWNIGVILLLLVMATAFVGYVLPWGQMSFWGATVITNLMSAVPYIGTSLVEWIWGGFSVDNATLTRFFTFHFLLPFAIMGVSMLHLLFLHETGSNNPTGLTSSTDKVPFHPYYSYKDLLGATLFTVILVTLALLFPNLLGDPENFTPANPLVTPPHIQPEWYFLFAYAILRSIPNKLGGVLALLFSILILMLIPLLHTSKQRGSAFRPPTQALFWALISNIIILTWIGGQPVEHPFIIIGQIASTSYFIIFLVLMPMTAKLENTLMKW

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue347

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB818751
EMBL· GenBank· DDBJ
BAO95327.1
EMBL· GenBank· DDBJ
Genomic DNA
AB818752
EMBL· GenBank· DDBJ
BAO95328.1
EMBL· GenBank· DDBJ
Genomic DNA
AB818755
EMBL· GenBank· DDBJ
BAO95331.1
EMBL· GenBank· DDBJ
Genomic DNA
AB818759
EMBL· GenBank· DDBJ
BAO95335.1
EMBL· GenBank· DDBJ
Genomic DNA
AB818766
EMBL· GenBank· DDBJ
BAO95342.1
EMBL· GenBank· DDBJ
Genomic DNA
AB818768
EMBL· GenBank· DDBJ
BAO95344.1
EMBL· GenBank· DDBJ
Genomic DNA
AB818769
EMBL· GenBank· DDBJ
BAO95345.1
EMBL· GenBank· DDBJ
Genomic DNA
AB818770
EMBL· GenBank· DDBJ
BAO95346.1
EMBL· GenBank· DDBJ
Genomic DNA
AB818771
EMBL· GenBank· DDBJ
BAO95347.1
EMBL· GenBank· DDBJ
Genomic DNA
AB818772
EMBL· GenBank· DDBJ
BAO95348.1
EMBL· GenBank· DDBJ
Genomic DNA
AB818775
EMBL· GenBank· DDBJ
BAO95351.1
EMBL· GenBank· DDBJ
Genomic DNA
AB818777
EMBL· GenBank· DDBJ
BAO95353.1
EMBL· GenBank· DDBJ
Genomic DNA
AB818778
EMBL· GenBank· DDBJ
BAO95354.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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