A0A060PJE6 · A0A060PJE6_9SAUR

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

134750100150200250300
TypeIDPosition(s)Description
Binding site51Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site65Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site150Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site164Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site169a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      cytb

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Lepidosauria > Squamata > Bifurcata > Unidentata > Scinciformata > Scincidae > Sphenomorphinae > Scincella

Accessions

  • Primary accession
    A0A060PJE6

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane51-71Helical
Transmembrane83-102Helical
Transmembrane108-134Helical
Transmembrane146-167Helical
Transmembrane197-218Helical
Transmembrane256-276Helical
Transmembrane291-308Helical
Transmembrane315-338Helical

Keywords

Interaction

Subunit

The cytochrome bc1 complex contains 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and probably 6 low-molecular weight proteins.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-177Cytochrome b/b6 N-terminal region profile
Domain178-347Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    347
  • Mass (Da)
    39,011
  • Last updated
    2014-09-03 v1
  • Checksum
    6FD5A267AF1566E1
FGSLLGMCLIIQVLTGLFLAMHYTANISSAFSSLAHICRDVQYGWLIRNIHANGASAFFICIYLHIGRGLYYGSYMYKETWNIGVILLLLVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYVGTSLVEWIWGGFSVHNATLTRFFMFHFLLPFIIMGASMLHLLFLHETGSNNPTGLSSNTDKIPFHPYFSYKDLLGASLLTLFLLSLALLFPYLLGDPENFTPANPLVTPPHIQPEWYFLFAYAILRSIPNKLGGVLALLFSILILMLIPLLHTSKQRGNAFRPPSQALFWALISNIFILTWIGGQPVEHPFIIIGQIASITYFINFLVLMPMTAKLENLLMKW

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue347

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB818833
EMBL· GenBank· DDBJ
BAO95409.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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