A0A060PJE6 · A0A060PJE6_9SAUR
- ProteinCytochrome b
- Genecytb
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids347 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Cofactor
Protein has several cofactor binding sites:
Note: Binds 2 heme groups non-covalently.
Note: Binds 2 heme groups non-covalently.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 51 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 65 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 150 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 164 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 169 | a ubiquinone (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | respiratory chain complex III | |
Molecular Function | metal ion binding | |
Molecular Function | ubiquinol-cytochrome-c reductase activity | |
Biological Process | mitochondrial electron transport, ubiquinol to cytochrome c |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCytochrome b
Gene names
Encoded on
- Mitochondrion
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Lepidosauria > Squamata > Bifurcata > Unidentata > Scinciformata > Scincidae > Sphenomorphinae > Scincella
Accessions
- Primary accessionA0A060PJE6
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 51-71 | Helical | ||||
Sequence: HANGASAFFICIYLHIGRGLY | ||||||
Transmembrane | 83-102 | Helical | ||||
Sequence: IGVILLLLVMATAFVGYVLP | ||||||
Transmembrane | 108-134 | Helical | ||||
Sequence: FWGATVITNLLSAIPYVGTSLVEWIWG | ||||||
Transmembrane | 146-167 | Helical | ||||
Sequence: FFMFHFLLPFIIMGASMLHLLF | ||||||
Transmembrane | 197-218 | Helical | ||||
Sequence: LLGASLLTLFLLSLALLFPYLL | ||||||
Transmembrane | 256-276 | Helical | ||||
Sequence: LGGVLALLFSILILMLIPLLH | ||||||
Transmembrane | 291-308 | Helical | ||||
Sequence: ALFWALISNIFILTWIGG | ||||||
Transmembrane | 315-338 | Helical | ||||
Sequence: FIIIGQIASITYFINFLVLMPMTA |
Keywords
- Cellular component
Interaction
Subunit
The cytochrome bc1 complex contains 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and probably 6 low-molecular weight proteins.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-177 | Cytochrome b/b6 N-terminal region profile | ||||
Sequence: FGSLLGMCLIIQVLTGLFLAMHYTANISSAFSSLAHICRDVQYGWLIRNIHANGASAFFICIYLHIGRGLYYGSYMYKETWNIGVILLLLVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYVGTSLVEWIWGGFSVHNATLTRFFMFHFLLPFIIMGASMLHLLFLHETGSNNPT | ||||||
Domain | 178-347 | Cytochrome b/b6 C-terminal region profile | ||||
Sequence: GLSSNTDKIPFHPYFSYKDLLGASLLTLFLLSLALLFPYLLGDPENFTPANPLVTPPHIQPEWYFLFAYAILRSIPNKLGGVLALLFSILILMLIPLLHTSKQRGNAFRPPSQALFWALISNIFILTWIGGQPVEHPFIIIGQIASITYFINFLVLMPMTAKLENLLMKW |
Sequence similarities
Belongs to the cytochrome b family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length347
- Mass (Da)39,011
- Last updated2014-09-03 v1
- Checksum6FD5A267AF1566E1
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: F | ||||||
Non-terminal residue | 347 | |||||
Sequence: W |