A0A059XLP9 · A0A059XLP9_9RHOD

  • Protein
    ATP-dependent zinc metalloprotease FtsH
  • Gene
    ftsH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

162850100150200250300350400450500550600
Type
IDPosition(s)Description
Binding site213-220ATP (UniProtKB | ChEBI)
Binding site434Zn2+ (UniProtKB | ChEBI); catalytic
Active site435
Binding site438Zn2+ (UniProtKB | ChEBI); catalytic
Binding site512Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentchloroplast
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATP-dependent peptidase activity
Molecular Functionmetalloendopeptidase activity
Molecular Functionzinc ion binding
Biological Processprotein catabolic process
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent zinc metalloprotease FtsH
  • EC number

Gene names

    • Name
      ftsH

Encoded on

  • Plastid

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Rhodophyta > Bangiophyceae > Bangiales > Bangiaceae > Pyropia

Accessions

  • Primary accession
    A0A059XLP9

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-26Helical
Transmembrane117-139Helical

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain205-344AAA+ ATPase

Sequence similarities

Belongs to the AAA ATPase family.
In the C-terminal section; belongs to the peptidase M41 family.
In the N-terminal section; belongs to the AAA ATPase family.
In the central section; belongs to the AAA ATPase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    628
  • Mass (Da)
    68,364
  • Last updated
    2014-09-03 v1
  • Checksum
    C6548B7FBB0420FA
MKLSWKTLLLWSLPIFVVGFFFWQGFLGPTTTDVGSNTASSRMTYGRFLEYLDMGWVKRVDLYENNHTAIVEAVGPELGNRVQRIRVELPASAPELITKLRKANVDLDAHPPKSTSAVWGLLGNLLFPLLLVGGLAFLFRRSNNASGGPGQAMSFGKSKALFQMEAKTGVVFNDVAGVEEAKEEFQEVVTFLKQPESFTAVGAKIPKGVLLVGPPGTGKTLLAKAIAGEASVPFFSISGSEFVEMFVGVGASRVRDLFKKAKDNAPCIVFIDEIDAVGRQRGTGVGGGNDEREQTLNQLLTEMDGFEGNTGVIVIAATNRADILDSALLRPGRFDRQVSVDVPDFRGRLAILEVHAKNKKMESKVSLDTIARRTPGFSGADLANLLNEAAILTARRRKNAMTMSEIDTSIDRVVAGMEGTPLIDSKSKRLIAYHEVGHAIIGSLLEHHDPVQKVTLIPRGQARGLTWFTPGDDQSLISRSQILARIVGALGGRAAEEIIFGDAEVTTGASNDLQQVTSMARQMVTRFGMSKIGPLSLESQGGDPFLGRGMGGGSEYSDEVATNIDKQVREIVSECYKEAKNIVADNRVVMDRLVDLLIEKETIEGSEFRDIVKEYTAIPDKNYYKSQF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KJ776836
EMBL· GenBank· DDBJ
AIA21355.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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