Essential maintenance is planned to begin on Tue Jan 28 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ during this time.

A0A059XBU7 · A0A059XBU7_9RHOD

  • Protein
    Protein translocase subunit SecA
  • Gene
    secA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

Catalytic activity

  • ATP + H2O + cellular proteinSide 1 = ADP + phosphate + cellular proteinSide 2.
    EC:7.4.2.8 (UniProtKB | ENZYME | Rhea)

Features

Showing features for binding site.

1884100200300400500600700800
TypeIDPosition(s)Description
Binding site83ATP (UniProtKB | ChEBI)
Binding site101-105ATP (UniProtKB | ChEBI)
Binding site491ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Cellular Componentplastid
Molecular FunctionATP binding
Biological Processintracellular protein transmembrane transport
Biological Processprotein import
Biological Processprotein targeting

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein translocase subunit SecA
  • EC number

Gene names

    • Name
      secA

Encoded on

  • Plastid

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Rhodophyta > Bangiophyceae > Bangiales > Bangiaceae > Pyropia

Accessions

  • Primary accession
    A0A059XBU7

Subcellular Location

Cell membrane
; Peripheral membrane protein
Cytoplasm
Membrane
; Peripheral membrane protein
Note: Distribution is 50-50.

Keywords

Interaction

Subunit

Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-668SecA family profile
Domain85-243Helicase ATP-binding

Sequence similarities

Belongs to the SecA family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    884
  • Mass (Da)
    101,440
  • Last updated
    2014-09-03 v1
  • MD5 Checksum
    EDD631F9053A1347A43C814121E93A6C
MFNFLFNSSNQRKINSYLPTIKKINALESEIQNLSDKALRTKSVEFKNRLKNGESLDNILIEAFSVVREAGFRVLGLRVFDVQIMGAIILHQGKIAEMKTGEGKTLVATLAGYLNALSGKGVHVVTVNDYLARRDSEWVGQIHKFLGLSVGLIQQDLPKAERKLAYQCDITYVTNSELGFDYLKDNMVLSMSEIVQNKFTFCIIDEVDSILIDEARTPLIISGPSEAPVEKYSKTQLLTNILVKDLHYEVDEKARNIILTDKGTLFCEEYLNINNLYDLDNPWVQYILNAIKAKELFTKDVHYIIRDNEVVIVDEFTGRIMSGRRWSDGLHQAIEAKEQVSIQQENQTYASITYQNFFLLYPKLSGMTGTAKTEESELDKIYNLEVICVPTHKPLRRQEFPDLVYSTEYRKWEAIADECYDMYRVGRPTLVGTTSVEKSELLSKLLTQYKIPHSLLNAKPENVEKESDIIAQAGRQSSVTIATNMAGRGTDIILGGNPNYIAKSILVDLLIGKTSVHNNHKLQQISIKTQISLNNILSTLEADLRSADFSVLDMEKKISIACEQVLIDDKLELQLRKAYQMIFKEYETIFSKEKQYVSQAGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSSRFFLSIDDNLLRIFGGNKIADLMQVLNVDNNTPMESTLLSKSLEAAQKKVEAYFYDTRKQVFEYDQVLNSQRQAIYAERRRILESSYPRDCVLQYAESTIEDIVNFWLTSKEKSEKVVNLNIKIKYLLNATDTFSISKELYGNPEELKKWIIEQVRINYDLREAYLEQIKPGLIRQLEKYYLLQQIDNAWKDHLQKMGALRDSIGWRSYGQQDPLVEYKNEAFNLFIEMITHVKHTVVYAILRSRLMIKND

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KJ776836
EMBL· GenBank· DDBJ
AIA21407.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help