A0A059JDF0 · A0A059JDF0_TRIIM

Function

function

Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionfarnesyl-diphosphate farnesyltransferase activity
Molecular Functionfarnesyltranstransferase activity
Molecular Functionsqualene synthase activity
Biological Processergosterol biosynthetic process
Biological Processfarnesyl diphosphate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Squalene synthase
  • EC number
  • Short names
    SQS
    ; SS

Gene names

    • ORF names
      H109_02354

Organism names

  • Taxonomic identifier
  • Strain
    • MR816
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Onygenales > Arthrodermataceae > Trichophyton

Accessions

  • Primary accession
    A0A059JDF0

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane419-443Helical

Keywords

  • Cellular component

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the phytoene/squalene synthase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    471
  • Mass (Da)
    54,754
  • Last updated
    2014-07-09 v1
  • Checksum
    1676D6229CDF877F
MKAAEIAYYLCHPQELRAIIQWTTYHEPVHTRDPSKETETEKKCYEFLKLTSRSFSAVIMELHPELLMPVCLFYLILRGLDTVEDDTSIPLETKEPILRGFKDILEEDGWTFTGNRPEEKDRELLVQFHNVITEFKKIKPAYKVIIKDITEKMGNGMADYIRRGEEDDEIVKTIEDYDLYCYYVAGLVGEGLTRLFVEAGFARPELLERPELFISMGRFLQKTNIIRDVREDHDDKRRFWPREIWSRHVKEFSDLFKPEFRQQALNCNSDMILNALSHVEDCIYYLSALREQSVFNFCCIPQTMAISTLELCFRNGTMFERNIKITKGTACRLMIDSTQNVRVACDVFRRYARAIHQKNTSKDPNFLKISMACGHVEKVIERIFPSQSPEAAARRLTNEKSPEQLAQDEADAEAKKDTMYIMLTIFGVLLFVTITMFFVAWLFGARFDLAIEEFKKGKIMPGPAQTHGGEL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AOKY01000177
EMBL· GenBank· DDBJ
KDB25814.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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