A0A059JDF0 · A0A059JDF0_TRIIM
- ProteinSqualene synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids471 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.
Catalytic activity
- 2 (2E,6E)-farnesyl diphosphate + H+ + NADH = 2 diphosphate + NAD+ + squalene
Cofactor
Pathway
Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | farnesyl-diphosphate farnesyltransferase activity | |
Molecular Function | farnesyltranstransferase activity | |
Molecular Function | squalene synthase activity | |
Biological Process | ergosterol biosynthetic process | |
Biological Process | farnesyl diphosphate metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSqualene synthase
- EC number
- Short namesSQS ; SS
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Onygenales > Arthrodermataceae > Trichophyton
Accessions
- Primary accessionA0A059JDF0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 419-443 | Helical | ||||
Sequence: MYIMLTIFGVLLFVTITMFFVAWLF |
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length471
- Mass (Da)54,754
- Last updated2014-07-09 v1
- Checksum1676D6229CDF877F
Keywords
- Technical term