A0A031FPB1 · A0A031FPB1_9MICO

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site142Transition state stabilizer
Active site146Proton acceptor
Binding site309Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      BW34_02363

Organism names

  • Taxonomic identifier
  • Strain
    • RIT293
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Microbacterium

Accessions

  • Primary accession
    A0A031FPB1

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link268↔294Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-145)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-16Polar residues
Region1-62Disordered
Domain179-475Plant heme peroxidase family profile

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    779
  • Mass (Da)
    84,470
  • Last updated
    2014-07-09 v1
  • Checksum
    8BF3585F38651D41
MSDRDPQAQSLGADATDVDQAVTPIDTPVDERGDGETRPRENTADGCPVIHSAPGADRANHGGQPHPTVGTANQVWWPNQLNLRILKKNPAVGNPVGEDFDYKAAFEALDLAAVKADIAEVLTTSQDWWPADFGNYGPLMIRMAWHSAGTYRATDGRGGGGTGQQRFAPLNSWPDNVNLDKARRLLWPVKKKYGQSLSWGDLMILAGNVALETMGFSTFGFGGGRPDVWEPDDDVYWGPETTWLADERYSGDRNLEKPLAAVQMGLIYVNPEGPNGEPDPLKSARDIRETFGRMGMDDEETVALIAGGHTFGKTHGAAPDTNVEANPEAAGIEEQGLGWKNNHGTGKGDDTITSGLEVTWTYHPTRWDNEFFHILYAYEWELMKSPGGGHQWRPINGAGADMVPLAHSDGRREPRMLTSDIALRTDPAYDAVSRRFKDDPVAFGDAFARAWFKLTHRDMGPVVRYLGPEVPQEELIWQDPVPAVDHELIDDADAALLKERILATGLTVSQLVSTTWAAASTFRGSDKRGGVNGARIRLAPQKDWEVNNPAQLQTVLAALEDVKAAFDAEQTGGKKVSLADLIVLAGNAGVEKAAKDAGVEATVPFHPGRTDASQEQTDELSFGYLEPAADGFRNYYGQNAVLPAEHHLIDKANLLTLSAPETTVLVGGLRALGANWDGSTYGVFTDRPGVLTNDVFVKLLDLGATWKPLDPGSHAFRGTAADGSEIGVGTRVDLVFSANSELRAVAEVYASDDAGEKFVRDFVAAWTKVTELDRFDLHA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-16Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JFYO01000007
EMBL· GenBank· DDBJ
EZP26031.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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